Non-Vitamin K Antagonist Oral Anticoagulants and Angioedema: A Cohort and Case-Crossover Study

ConclusionsOur estimates were inconsistent with substantial short-term relative increases in the rate of angioedema associated with oral anticoagulant therapy.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research

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AbstractThe management of patients with atrial fibrillation (AF) has rapidly changed with increasing use of non-vitamin K antagonist oral anticoagulants (NOACs) and changes in the use of rhythm control therapy. The prevention of thromboembolic events European Registry in Atrial Fibrillation Prolongation Registry (PREFER Prolongation) enrolled consecutive patients with AF on NOACs between 2014 and 2016 in a multicentre, prospective, observational study with one-year follow-up, focusing on the time of introduction of NOACs. Overall, 3783 patients were enrolled, with follow-up information available in 3223 (85%). Mean age was...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
AbstractSerial changes of electrocardiograms (ECG) could be used to assess their clinical features in atrial septal defects (ASD) after transcatheter closure together with other clinical parameters. We retrospectively studied 100 ASD patients who underwent transcatheter closure. Complications of persistent atrial fibrillation occurred in five ASD patients, and they were excluded. We divided the other 95 patients according to PQ intervals before closure (normal:  
Source: Heart and Vessels - Category: Cardiology Source Type: research
Publication date: Available online 18 September 2020Source: Revista Española de Cardiología (English Edition)Author(s): Nuria Rivas-Gándara, Jaume Francisco-Pascual
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
In this issue of the Seminars, Ni and colleagues report outcomes of the first series of patients treated with minimally invasive left atrial appendage excision (LAAE) and atrial fibrillation (AF) ablation for secondary prevention of thromboembolic stroke1. Although the follow up period is relatively short, the authors are to be commended for demonstrating procedural safety using video assisted thoracoscopic surgery (VATS) AF ablation and LAAE, in addition to ensuring meticulous follow up including electrocardiographic Holter monitoring and computed tomography angiography (CTA) for assessment of completeness of LAAE in this...
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ADULT – Commentary Source Type: research
AbstractObjectiveAtrial functional mitral regurgitation (AFMR) is caused by atrial fibrillation and left atrial enlargement. Our study aimed to evaluate the efficacy of left atrial plication (LAP) for AFMR.MethodsOf 1164 mitral valve surgery patients at our hospital from January 2000 to May 2019, 22 patients underwent surgery for AFMR. Our retrospective analysis divided the patients with AFMR into two groups according to whether LAP was performed (LAP  + group,n = 9; LAP − group,n = 13). Mitral valve angle (MV angle) (horizontal inclination of mitral valve) was ...
Source: General Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
A 64-year-old man diagnosed with persistent atrial fibrillation underwent a first ablation process. The ablation strategy consisted of liner ablations, including the roof, bottom, and mitral isthmus, as well as pulmonary vein isolation. Ethanol infusion of 5 mL into the Marshall vein was performed prior to pulmonary vein isolation while locating the AdvisorTM HD grid-mapping catheter (Abbott, St Paul, Minnesota, USA) and checking the real-time voltage map using the EnSiteTM LiveView Dynamic Display (Abbott).
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
AbstractThe last several years have seen increasing interest in understanding cachexia, muscle wasting, and physical frailty across the broad spectrum of patients with cardiovascular illnesses. This interest originally started in the field of heart failure, but has recently been extended to other areas such as atrial fibrillation, coronary artery disease, peripheral artery disease as well as to patients after cardiac surgery or transcatheter aortic valve implantation. Tissue wasting and frailty are prevalent among many of the affected patients. The ageing process itself and concomitant cardiovascular illness decrease lean ...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
AbstractBackgroundSilent cerebral microembolic events (SCE) after duty-cycled ablation of atrial fibrillation using PVAC have been detected by cerebral magnet resonance imaging (MRI) in a substantial number of patients.The purpose of this study was to investigate if uninterrupted oral anticoagulation with non-vitamin K antagonists (NOACs) compared with vitamin K antagonists (VKA) affects the incidence of SCE after pulmonary vein isolation (PVI) using PVAC Gold.MethodsEighty-four consecutive patients (62 ± 15 years, 58% male) undergoing a first PVI were prospectively enrolled. Of these, 42 were on VKA and 42 on unint...
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
This study aimed to evaluate the prevalence of individual cardiac and non ‐cardiac coexisting morbidities both in the overall HF population and in the subgroup of HF patients with a single coexisting morbidity, stratified by left ventricular ejection fraction (LVEF) categories, as a measure of the relative contribution of each co‐morbidity to the pathogenesis of HF.Methods and resultsThis is a prospective, observational study, in which unselected ambulatory patients with chronic HF visiting the HF clinic of a tertiary university hospital from January 2016 to January 2019 were classified according to baseline LVEF into ...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Short Communication Source Type: research
Atrial arrhythmias, i.e., intra-atrial reentrant tachycardia and atrial fibrillation, are a leading cause of morbidity and hospitalizations in adults with congenital heart disease (CHD). Little is known about their effect on quality of life and other patient-reported outcomes (PROs) in adults with CHD.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
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