Whole-exome sequencing of familial esophageal squamous cell carcinoma identified rare pathogenic variants in new predisposition genes

ConclusionTogether, we identified new potential esophageal squamous cancer predisposition variants in genes which may have a role in cancer and are involved in chromatin remodeling and cell-cycle pathway, which could increase the risk of ESCC.

Source: Clinical and Translational Oncology - July 17, 2019 Category: Cancer & Oncology Source Type: research