Descriptive study of suspected congenital Zika syndrome cases during the 2015-2016 epidemic in Brazil

CONCLUSIONS: Although ZIKV was not confirmed to cause the congenital malformations, this study demonstrated that the clinical and epidemiological findings associated with a STORCH exclusion strengthened the CZS diagnosis. The suspected cases in MT occurred simultaneously with the first CZS cases reported in Brazil, suggesting ZIKV circulation in the study region during the same period.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research

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ConclusionHemiplegic spontaneous cervical EDH occurs very rarely. It is often misdiagnosed as ischemic stroke and is likely to be administered with thrombolytic agents, making the patient's symptoms worse. Early diagnosis and rapid management of cervical EDH increase the likelihood of complete recovery of the patient's symptoms. Therefore, if there are unilateral weakness and neck pain without cranial nerve dysfunction and there is no evidence of stroke in the brain imaging, spinal EDH should be considered.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
Authors: Reinhart J, Willett M, Gibbs N Abstract Psoriasis is a common dermatologic condition with a variety of morphologic presentations. These variations include the less common hyperkeratotic form, psoriasis ostracea, defined as having pronounced adherent scales resembling an oyster shell. Of the ostraceous cases that have been reported in the literature, many occur as generalized outbreaks in patients with long-standing history of psoriasis. Rarely does this remarkable variant occur as a direct flare from a cutaneous insult. In these situations, when a pre-existing dermatosis appears in response to a traumatic ...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
This study aimed to assess, by molecular studies, the virulent nature of some Bacillus strains in live edible snails (Achatina achatina) sold in Nigerian markets and to ascertain the survival of bacilli during culinary preparation. Results showed that isolates with high virulence potentials were B. thuringiensis and two strains of B. cereus (GenBank accession numbers: MK530172, MK530171 and MK530202). The nheb gene was detected in all three isolates, while B. thuringiensis strain was found to possess hbla, nhea, nheb and cytk genes for enterotoxins often implicated in diarrhoea cases. Most isolates were resistant to chlora...
Source: Food Control - Category: Food Science Source Type: research
Publication date: Available online 12 August 2019Source: Food ControlAuthor(s): Jiayin Chen, Xiyang Wu, Gloria Sánchez, Walter RandazzoAbstractBerries have frequently been cited as causing gastroenteritis and acute hepatitis outbreaks due to enteric virus contamination, including human norovirus and hepatitis A virus (HAV). Model experiments were performed to evaluate the potential use of viability RT-qPCR to assess the thermal inactivation of norovirus genotype I (GI), GII, and HAV on raspberries, blueberries and strawberries. Initially, two viability markers, platinum chloride and propidium monoazide (PMAxx™...
Source: Food Control - Category: Food Science Source Type: research
Publication date: Available online 8 August 2019Source: Food ControlAuthor(s): Hossein Daryaei, Qian Sui, Hui Liu, André Rehkopf, Walter Peñaloza, Andreas Rytz, Yuqi Luo, Jason WanAbstractTwenty-two Shiga toxin-producing Escherichia coli (STEC) strains and six potential surrogates (E. coli strains K12 and P1, Listeria innocua, Lactobacillus plantarum, Bifidobacterium lactis, and Enterococcus faecium) were screened in wheat flour at two water content levels of 8 and 13% (0.25 and 0.55 water activities) for survival at 6°C and resistance to a heat treatment at 82°C for 5 min. The results showed that the...
Source: Food Control - Category: Food Science Source Type: research
CONCLUSION: The study showed poor level of preparedness for Lassa fever and recommended routine training of HCWs on emergency preparedness. PMID: 31422994 [PubMed - in process]
Source: Journal of Health Care for the Poor and Underserved - Category: International Medicine & Public Health Authors: Tags: J Health Care Poor Underserved Source Type: research
This study investigated the experiences of the Kaingang and Guarani Indigenous peoples from the South of Brazil regarding the effects of cultural changes on their food systems and oral status. Focus groups were conducted in each tribe and the methodological framework grounded theory was adopted. The development of categories occurred with reference to Pierre Bourdieu's work. Four themes emerged from the analysis: 1. Contemporary Indigenous identities; 2. Perceptions of food systems; 3. Shared knowledge in the orientation of differentiated assistance in oral health; and 4. Ethnic cultural capital in conflict. The food trans...
Source: Journal of Health Care for the Poor and Underserved - Category: International Medicine & Public Health Authors: Tags: J Health Care Poor Underserved Source Type: research
Publication date: 2019Source: Advances in Virus Research, Volume 104Author(s): Melina Vallbracht, Marija Backovic, Barbara G. Klupp, Felix A. Rey, Thomas C. MettenleiterAbstractMembrane fusion is a fundamental biological process that allows different cellular compartments delimited by a lipid membrane to release or exchange their respective contents. Similarly, enveloped viruses such as alphaherpesviruses exploit membrane fusion to enter and infect their host cells. For infectious entry the prototypic human Herpes simplex viruses 1 and 2 (HSV-1 and -2, collectively termed HSVs) and the porcine Pseudorabies virus (PrV) util...
Source: Advances in Virus Research - Category: Virology Source Type: research
Publication date: 2019Source: Advances in Virus Research, Volume 104Author(s): Mitsuhiro Nishimura, Yasuko MoriAbstractIn this chapter, we present an overview on betaherpesvirus entry, with a focus on human cytomegalovirus, human herpesvirus 6A and human herpesvirus 6B. Human cytomegalovirus (HCMV) is a complex human pathogen with a genome of 235 kb encoding more than 200 genes. It infects a broad range of cell types by switching its viral ligand on the virion, using the trimer gH/gL/gO for infection of fibroblasts and the pentamer gH/gL/UL128/UL130/UL131 for infection of other cells such as epithelial and endothelial...
Source: Advances in Virus Research - Category: Virology Source Type: research
Conclusions Apart West Nile virus (78), thousands of congenital microcephaly cases, fetal brain tissue damage and neurological syndromes have been associated with ZIKV infection. Unfortunately, the epidemics of this mosquito born, and a relative stable virus is on a rise. Although congenital microcephaly is a rare disorder however, due to lack of standardized diagnostic test facilities, the incidence in the geographically widespread ZIKV epidemic regions is higher. Animals studies showed that ZIKV is a neurotropic virus. It directly targets the developing embryonic brain cells by inducing apoptosis, cell-cycle arrest, and...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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