MRI-based tumour control probability in skull-base chordomas treated with carbon-ion therapy

Particle therapy makes use of protons and heavier ions to improve geometrical and biological efficacy in terms of dose distribution, with respect to photons, thus enabling tumour dose escalation whilst sparing the surrounding healthy tissues. Although protons have a biological effectiveness comparable to photons, this is higher for heavy ions [1]. In particular, carbon-ion radiotherapy (CIRT) has been found to perform well with radioresistant tumours close to organs at risk [2], such as chordoma tumours [3].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research