Cancer Stem Cells: From Historical Roots to a New Perspective.
This article mentions key results that lead to a new perspective where cancer stem cells are primarily seen as cells exhibiting increased epigenetic plasticity and increased gene expression variability. This perspective suggests new therapeutical interventions consisting in stabilizing gene expression to control cancer cell proliferation and prevent stochastic gene expression variations that could lead to therapeutic resistance.
PMID: 31308849 [PubMed]
Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
More News: Cancer | Cancer & Oncology | Carcinoma | Embryonal Carcinoma | Genetics | History of Medicine | Men | Stem Cell Therapy | Stem Cells