Association between pre-diabetes, type 2 diabetes and trabecular bone score: The Vietnam Osteoporosis Study

Type 2 diabetes (T2D) is associated with higher bone mineral density (BMD) [1], which is supposed to be associated with lower risk of fracture in the general population. However, individuals with T2D actually have higher risk of fracture, particularly hip fracture [2] and vertebral fracture [3]. Our previous study showed that approximately half of all fractures occurred in those do not have low BMD [4]. This suggested that fractures in patients with diabetes may result from alterations in skeletal properties or bone quality not captured by dual-enery X-ray absorptiometry (DXA)- derived BMD [5].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research