Pathological assessment of cytoreductive surgery specimens and its unexplored prognostic potential-a prospective multi-centric study

ConclusionsPathological evaluation provides a more accurate and objective assessment of extent and distribution of peritoneal disease. Lymph node involvement in relation of peritoneal disease is common. The morphological presentation of PM in ovarian cancer and mucinous appendiceal tumors merits evaluation of more extensive resections in these patients. Standardized methods of synoptic reporting of CRS specimens could help capture vital prognostic information that may in future influence how these patients are treated.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research

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Conclusion: Endoscopists at our institutions met/exceeded the quality metrics in the first half of each year from the beginning of the study. Routine reporting may maintain, but not improve, outcomes. Long-term studies to determine if periodic feedback to endoscopists improves the quality of endoscopy as per national standards for detection of early colorectal cancers are required. PMID: 31428145 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
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Source: Cancer Nursing - Category: Nursing Tags: DEPARTMENTS: Guest Editorial Source Type: research
Conclusions Cancer coordinators encounter cognitive, practical, and relational topics that impact their system-focused activities. Adopting a salutogenic focus can help CCs mobilize resources needed to turn challenges into facilitators for system-level work. Implications for Practice Cancer care coordination cannot be undertaken by CCs alone. Cancer coordinators' embedding in multidisciplinary teams, common systems for care provision, meaningful work relations, and professionals' commitment to cancer care represent important facilitators for CCs' system-focused tasks.
Source: Cancer Nursing - Category: Nursing Tags: ARTICLES Source Type: research
Conclusion Results provide insights into modifiable risk factors for morning fatigue. These risk factors can be used to develop more targeted interventions. Implications for Practice Patients in the high and very high morning fatigue classes experienced high symptom and comorbidity burdens and significant decrements in functional status. Using this information, clinicians can identify patients who are at an increased risk for higher levels of morning fatigue and prescribe interventions to improve this devastating symptom.
Source: Cancer Nursing - Category: Nursing Tags: ARTICLES Source Type: research
Conclusion Medication administration is an activity of great responsibility for nursing; however, in order to achieve a decrease in medication errors, prevention strategies are necessary for the whole health team. Implications for Practice Practice improvements are needed including establishing institutional drug administration protocols and keeping them updated, using a computerized prescription system, and promoting patient safety with staff.
Source: Cancer Nursing - Category: Nursing Tags: ARTICLES Source Type: research
Background Gynecologic cancer can create hopelessness and death anxiety and alter the lifestyle of the affected women and their caregivers. Perceived social support may facilitate coping with this illness. Objective The aim of this study was to determine whether hospitalized patients with gynecologic cancer and their caregivers differ in feelings of hopelessness and death anxiety and how those conditions may be related to their social support. Methods Two hundred patients with gynecologic cancer and their 200 caregivers from 1 university hospital were enrolled in this descriptive correlational study. Study measures...
Source: Cancer Nursing - Category: Nursing Tags: ARTICLES Source Type: research
AbstractObjectivesThe goal was to determine the incidence and clinical behavior of peritoneal metastases (PM) in patients with colorectal cancer undergoing potentially curative surgery, comparing patients with extensive loco ÔÇÉregional lymph node involvement (pN2) with those who have serosal involvement (pT4), a known risk factor for developing PM.MethodsA retrospective analysis of a prospectively maintained database was performed. All patients with pT4 and pN2 were included in the analysis. The diagnostic criteria were the finding of PM during surgery with biopsy confirmation as well as imaging features suggestive of PM ...
Source: Colorectal Disease - Category: Gastroenterology Authors: Tags: Original Article Source Type: research
CONCLUSIONS: Evidence regarding the incidence of recurrent PM after curative surgery for colorectal cancer is poor. Situations at higher risk of recurrent PM are synchronous PM, synchronous isolated ovarian metastases, perforated primary tumor with serosa invasion and mucinous histological subtype. PMID: 28540831 [PubMed - as supplied by publisher]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
CONCLUSION: More extended cytoreductive surgery is needed in case of peritoneal carcinimatosis from ovarian cancer. In case of PC from mucinous adenocarcinoma of the appendix, it's difficult to calculate the extent of the disease and avoid unnecessary surgical excisions. More data is needed to confirm the above. KEY WORDS: Cytoreductive surgery, Gallbladder, HIPEC, Peritoneal carcinomatosis, Round ligament of the liver. PMID: 26344805 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Conclusion Our study suggests that T4 stage, high-risk macroscopic and high-risk microscopic features at time of primary diagnosis identifies the majority of CRC patients who later develop PM. This provides support for a selective second-look protocol in such patients to enable early identification and, potentially, ‘prevention’ of CRC PM.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
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