Active pulmonary tuberculosis presenting with acute respiratory failure

We report the clinical course of four patients with active pulmonary tuberculosis presenting with acute respiratory failure who were treated successfully. Four patients with active pulmonary tuberculosis (PTB) presenting with respiratory failure are reported here. Bronchogenic PTB, simulating an acute febrile illness or diffuse interstitial lung disease with short duration of symptoms, as a cause of acute respiratory failure is less recognized. If diagnosed and treated early, it has good prognosis. Three of the four patients presented here had an acute presentation with fever, dyspnoea, and hypoxemia with diffuse infiltrative lesions on radiography, and the other younger patient presented predominantly with lobar consolidation. These patients presenting with respiratory failure required intensive care management, and a diagnosis was made with bronchoalveolar lavage fluid and transbronchial lung biopsy. All four patients promptly received antitubercular therapy, showed clinicoradiological improvement, and were stable at 1 year follow up.
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Series Source Type: research

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CONCLUSIONS: The current clinical case emphasizes issues that a physician may encounter in the differential diagnostics of amiodarone-induced lung toxicity with other lung diseases. PMID: 30594249 [PubMed - in process]
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research
Conclusions: The isolation of MAC in bronchoscopic samples when it is not accompanied by clinical context should be interpreted with cautionThere are frequent isolations in patients with other diseases as cancer or interstitial lung disease (ILD) of uncertain meaning
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
We report the case of a 31-year-old male with a history of sniffing hydrogenated oil, presenting with a non-resolving pneumonia. PMID: 30152655 [PubMed - in process]
Source: Indian Journal of Chest Diseases and Allied Sciences - Category: Respiratory Medicine Tags: Indian J Chest Dis Allied Sci Source Type: research
We report a case of PLCH masquerading as Atypical Mycobacterium Gordonae infection.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Conclusion: Even though the size of our study population was small, the positive rate of 7.4% was like or lower than those in other lung cancer screening studies. Early lung cancer was detected using LDCT screening in one participant. Lung-RADS may be applicable to participants in Korea, where pulmonary tuberculosis is endemic. PMID: 29962887 [PubMed - in process]
Source: Korean J Radiol - Category: Radiology Authors: Tags: Korean J Radiol Source Type: research
AbstractPneumonia is a common cause of morbidity and mortality in adults in the United States. While pneumonia classically presents with a fever, cough, and shortness of breath, the presentation can vary widely in adults. This review evaluates history and physical examination findings of pneumonia and several conditions that mimic pneumonia. Pneumonia is a potentially deadly disease. History and examination findings are variable in pneumonia, and many conditions mimic pneumonia. These conditions include pulmonary embolism, diffuse interstitial lung disease, endocarditis, vasculitis, diffuse alveolar hemorrhage, acute decom...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
Source: International Journal of Tuberculosis and Lung Disease - Category: Respiratory Medicine Authors: Tags: ORIGINAL ARTICLES Source Type: research
Conclusion: ILD are the disorders that are frequently unrecognized. More commonly the confusion is with TB which is over-diagnosed due to much reliance on chest x-ray findings and clinical diagnosis. Thorough knowledge about ILD should be provided to the primary care physicians, especially in countries with high TB burden, so that to limit unnecessary treatment with anti-tuberculous drugs and early referral to ILD clinic.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
Introduction: The aim of this study was to evaluate the prevalence of latent tuberculosis infection (LTBI) in our interstitial lung disease (ILD) patients. Methods: Patients with ILD were tested by using a commercial test QuantiFERON®-TB-Gold In Tube (QFT) at the time of initial diagnosis, before any immunomodulatory drug was initiated. Those patients with a historical or active TB were excluded, as were any with an equivocal QFT result. They were compared with 272 control cases who had a normal chest x-rays or thoracic CT, and no history of TB. Comparisons were classified by age (
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Diffuse Parenchymal Lung Disease Source Type: research
We report herein the case of a patient with primary immunodeficiency revealed by pneumocystosis, which could have been misdiagnosed as an idiopathic acute exacerbation of ILD.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interstitial and orphan lung disease, Respiratory infections and tuberculosis Original Articles: Research letters Source Type: research
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