Stevie Wonder To Receive Kidney Transplant: Is This An Emergency?
Stevie Wonder will receive a kidney transplant in the coming months. Kidney disease is surprisingly common, especially in minority populations. Kidney donation can be performed from a living donor, and can be scheduled as opposed to performed as an emergency surgery.
Publication date: Available online 22 August 2019Source: Actas Urológicas Españolas (English Edition)Author(s): L.E. Garcia, J. Gonzalez, G. Serena, M. Ammar Al-Nuss, M. Morsi, W. DeFaria, G. Ciancio
AbstractBackgroundRecently, living-donor kidney transplantation from marginal donors has been increasing. However, a simple prediction model for graft function including preoperative marginal factors is limited. Here, we developed and validated a new prediction model for graft function using preoperative marginal factors in living-donor kidney transplantation.MethodsWe retrospectively investigated 343 patients who underwent living-donor kidney transplantation at Kyushu University Hospital (derivation cohort). Low graft function was defined as an estimated glomerular filtration rate of
AbstractIschemia-reperfusion injury (IRI) is an inevitable consequence of kidney transplantation (KT). The aim of our study was to investigate the protective effect of a glycogen synthase kinase 3 β (GSK-3β) inhibitor against cold IRI in a rat renal transplantation (RT) model and a rat cold-IRI model through the toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88)/nuclear factor κ-light-chain-enhancer of the activated B cell (NF-κB) signaling pathway. We treated Sprague D awley (SD) rats in the RT and cold-IRI models with 5 mg/kg and 1 mg/kg, respectively, of the GSK-3β...
In the above-stated article, the bold data in Table 1 have been revised.
A 39-year-old male, live-related renal transplant recipient with stable graft function presented with multiple painless, non-itchy, papular lesions over the midback region. Three months later, these lesions became multiple abscesses with pus exudation (Figure 1). The patient had a history of injury to his midback from the sharp edge of cement stairs, which caused an abrasion. He had received a thymoglobulin induction and was on prednisolone, tacrolimus, and azathioprine. The microscopic examination of KOH mount of pus revealed multiple, septate, branch ing, brown-pigmented hyphae with thick-walled vesicular swellings...
Contrast-induced nephropathy (CIN) is a dreaded complication of peripheral vascular interventions (PVIs), especially for kidney transplant recipients (KTRs). However, the incidence of and factors associated with CIN in that population of patients have not been studied.
A 60-year-old African American male on immunosuppression for recent kidney transplant, who initially complained of multiple symptoms, including laryngitis, productive cough, nausea, vomiting, diarrhea, fatigue, and rib pain, was admitted and intubated secondary to critical hemorrhagic shock from frank alveolar hemorrhage on bronchoalveolar lavage. This was initially thought to be vasculitic in nature by primary team and consultants following a broad and unremarkable workup, including BAL cultures, stains, and cytology.
Authors: Heidary Rouchi A PMID: 31422396 [PubMed - in process]
CONCLUSION: Glucocorticoids is the the mainstay of treatment. Therenal function tests, of the vast majority of patients, normalizedwith treatment. Relapse may occur, so a follow-up over a longperiod of time is required. A high index of suspicion is neededfor diagnosis in asymptomatic patients. PMID: 31422391 [PubMed - in process]
CONCLUSION: Although we did not find a statistically significantrelationship between vitamin D levels and the CMV infection, CMVinfected patients had lower vitamin D level compared with noninfectedrecipients, hence vitamin D deficiency can be consideredas a risk factor for CMV reactivation after renal transplantation. PMID: 31422387 [PubMed - in process]