Risk of acute myocardial infarction and ischemic stroke in patients with asthma exacerbation: A population-based, self-controlled case series study

Publication date: Available online 16 July 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Yoshihiko Raita, Carlos A. Camargo, Mohammad Kamal Faridi, David F.M Brown, Yuichi J. Shimada, Kohei HasegawaAbstructBACKGROUNDPatients with asthma have a high incidence of acute myocardial infarction and ischemic stroke.OBJECTIVEWe aim to investigate the acute effect of asthma exacerbation on these cardiovascular events.METHODSUsing population-based inpatient data of three geographically-diverse U.S. states (Florida, Nebraska, and New York) during 2011-2014, we conducted a self-controlled case series study of adults (aged ≥40 years) hospitalized with asthma exacerbation. The primary outcome was a composite of acute myocardial infarction and ischemic stroke. We used conditional Poisson regression to compare each patient’s incidence rate of the outcome during three sequential risk periods (1-7, 8-14, and 15-28 days after asthma exacerbation) with that of reference period (i.e., summed period before and after the three risk periods).RESULTSWe identified 4,607 adults hospitalized for asthma exacerbation who had a first episode of acute myocardial infarction or ischemic stroke. During the reference period, the incidence rate of acute myocardial infarction or ischemic stroke was 25.0/100 person-years. Compared with the reference period, the incidence rate significantly increased during the first risk period (129.1/100 person-years), with a correspon...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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Publication date: December 2019Source: Results in Physics, Volume 15Author(s): Cleverson FilgueirasAbstractIn this letter, we analyze a conceptual design for the operation of an Otto cycle heat machine driven by adiabatic modifications on the electronic effective mass. Such tailoring of it can be implemented, for instance, via the application of external electron fields in some materials, as in Gallium Nitride (GaN). We show that due both the energy quantization on this structure and the adiabatic transformation of the effective mass, the machine performance can be improved. The realization of classically inconceivable Ott...
Source: Results in Physics - Category: Physics Source Type: research
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Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Heart disease Heart attack Stroke Health Pharmaceuticals industry Drugs Science Iran Source Type: news
Authors: Ito A, Ishiguro T, Takaku Y, Kagiyama N, Kamei K, Takayanagi N Abstract A 42-year-old man with asthma presented in 2007 with chest infiltration and productive cough. Pycnoporus sanguineus and Perenniporia tephropora were repeatedly isolated from sputum and bronchial washing fluids. Because we lacked immunologic evidence, we could not diagnose him with allergic bronchopulmonary mycosis (ABPM) due to these basidiomycetous fungi. At that time, serum-specific IgE and IgG against Schizophyllum commune findings were negative. Inhaled beclomethasone/salmeterol improved his condition. Seven years later, mucous plu...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
AbstractTo study variables associated with Emergency Department (ED) utilization among pediatric patients with asthma in a Federally Qualified Health Center (FQHC). We analyzed Electronic Health Record (EHR) data in a retrospective cohort study of patients with asthma between ages 2 and 18 who received primary care at a FQHC. The primary outcome studied was a visit to the ED at Ann and Robert Lurie ’s Children’s Hospital (LCH) for an acute visit related to asthma. Univariate analyses and a multiple logistic regression were performed to study the effect of demographic and clinical variables on ED utilization. Of...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
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Source: ACSMs Health and Fitness Journal - Category: Sports Medicine Tags: Departments: Take Ten Source Type: research
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Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
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Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
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Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Cervical spondylosis may lead to spinal cord compression, poor vascular perfusion, and ultimately cervical myelopathy. The process whereby chronic compression may cause spinal cord damage has not been fully understood. However, multiple mechanisms such as inflammation, apoptosis, and vascular variations, are thought to be responsible for the neuronal loss, axonal degeneration, and myelin impairment seen in cervical spondylotic myelopathy (CSM). Studies reported a beneficial effect of renin-angiotensin system (RAS) blockers in the central nervous system, particularly in brain inflammation and stroke, but data on their influ...
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