Febuxostat Desensitization in a Patient with Previous Stevens-Johnson Syndrome and HLA-B*58:01 Genotype.

We describe the first case, to our knowledge, of successful desensitization to febuxostat in a young high-risk patient of Filipino descent with HLA-B*58:01 positive genotype and previous drug-induced Stevens-Johnson Syndrome (SJS), with 2 subsequent episodes of a morbilliform rash with repeat exposures to febuxostat.
PMID: 31308200 [PubMed - as supplied by publisher]

Source: J Rheumatol - July 14, 2019 Category: Rheumatology Authors: Tana T, Vadas P Tags: J Rheumatol Source Type: research