The effect of Heweijiangni-decoction on esophageal morphology in a rat model of OVA-induced visceral hypersensitivity followed by acid exposure.

In this study, we observed the effect of HWJND on esophageal morphology in a rat model of ovalbumin (OVA)-induced visceral hypersensitivity followed by acid exposure. Esophageal morphology was assessed by measuring the extent of dilated intercellular spaces (DIS), desmosome disruption, and mitochondrial fragmentation. HWJND in low, moderate, and high doses relieved DIS and desmosome disruption in esophageal epithelium compared with model group (P<0.05 for all doses). In addition, HWJND in high dose protected mitochondria from fragmentation (P<0.05). Other findings suggest that DIS and mitochondrial fragmentation are independent events, and that omeprazole protects mitochondria. Overall, HWJND significantly resists esophageal morphology changes in OVA-induced and acid exposure rat model. PMID: 31304910 [PubMed - in process]
Source: Cellular and Molecular Biology - Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

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Publication date: October 2019Source: Molecular Immunology, Volume 114Author(s): Jun Chen, Shengjun Lu, Xiufang Weng, Zhihui Liang, Xiongwen WuAbstractHLA-A2 is the most common serological HLA type among all ethnic groups. Through advances in DNA typing, more than 800 subtypes of HLA-A2 have been identified, and the existence of heterogeneity of antigen specificity among the HLA-A2 subtypes has been suggested by retrospective analyses of allogeneic transplantation patients and by studies of antigen amino acid structure. However, prior to this study, the antigenicity of a given subtype or the mismatch extent between two giv...
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
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Publication date: Available online 24 August 2019Source: Food Quality and PreferenceAuthor(s): Rongduo Liu, Klaus G. GrunertAbstractThis paper focuses on Chinese elderly’s life satisfaction with food, a specific and important domain of Chinese people’s daily life, with two purposes: first, to investigate the relationship between satisfaction with food-related life and life satisfaction among Chinese elderly; second, to segment Chinese elderly based on their beliefs about food health, safety, freshness and taste, and profile them by their life satisfaction, satisfaction with food-relate life, food-related goals,...
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Publication date: Available online 24 August 2019Source: Process BiochemistryAuthor(s): Binbin Wang, Qiaozhi Song, Fangkun Zhao, Huazhi Xiao, Zhijiang Zhou, Ye HanAbstractAn exopolysaccharide (EPS)-producing bacterial strain, PC, was isolated from pickled Chinese cabbage and identified as Leuconostoc pseudomesenteroides. EPS yield was up to 30.5 g/L when bacteria were cultivated in Man-Rogosa-Sharpe (MRS) medium containing 5% sucrose at 30°C for 48 h. Further analysis by gas chromatography, high performance size exclusion chromatography, and nuclear magnetic resonance revealed that the EPS consisted of glucose with &al...
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Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
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Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Augustina Ursino Case Reports on Vaccine Injury Human Top Stories truth about vaccines Source Type: blogs
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