Causes of late transplant failure in cyclosporine-treated kidney allograft recipients

ConclusionsProlonged use of cyclosporine may expose to several dose-related adverse events and may contribute to the development of allograft dysfunction but it does not necessarily cause relentless, progressive transplant failure if patients are carefully and consistently monitored during the follow-up.
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research

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Publication date: October 2019Source: Molecular Immunology, Volume 114Author(s): Jun Chen, Shengjun Lu, Xiufang Weng, Zhihui Liang, Xiongwen WuAbstractHLA-A2 is the most common serological HLA type among all ethnic groups. Through advances in DNA typing, more than 800 subtypes of HLA-A2 have been identified, and the existence of heterogeneity of antigen specificity among the HLA-A2 subtypes has been suggested by retrospective analyses of allogeneic transplantation patients and by studies of antigen amino acid structure. However, prior to this study, the antigenicity of a given subtype or the mismatch extent between two giv...
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
Authors: Lin D, Yong J, Ni S, Ou W, Tan X Abstract Objective: Study the association of adropin and hypertensive disorders complicating pregnancy (HDCP). Methods: Patients with HDCP were matched with normotensive women (47 pairs). Adropin concentrations were detected by enzyme-linked immunosorbent assay. Results: Compared with the controls, the serum adropin levels were lower in the HDCP group (P
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
Publication date: Available online 24 August 2019Source: MethodsXAuthor(s): Cassiano Felippe Gonçalves-de-Albuquerque, Marcos Roberto Colombo Barnese, Mariana Alves Soares, Mauro Velho Castro Faria, Adriana Ribeiro Silva, Hugo Caire Castro Faria Neto, Patrícia Burth, Mauricio Younes-IbrahimAbstractCirculating non-esterified fatty acids (NEFA) are toxic to mammalian cells. They increase in diseases such as diabetes and sepsis. Herein we propose a serum albumin-fatty acid saturation test. •We based our test on three methodologies: isoelectric focusing (IF) of human plasma albumin, staining proteins after i...
Source: MethodsX - Category: Science Source Type: research
Authors: Nicholson P, Lenck S, Kucharczyk W, Mendes-Pereira V Abstract There is increasing interest in venous sinus stenting in patients with idiopathic intracranial hypertension who are refractory to medical therapy. Often the transverse sinus stenoses are bilateral, however, and there is no clear evidence for whether we should stent one or both sides in these patients. Our practice is to first stent one side, and in this brief case report, we demonstrate complete resolution of the contralateral stenosis in one such patient who underwent stenting. Her symptoms also completely resolved, and so this case highlights ...
Source: Interventional Neuroradiology - Category: Radiology Tags: Interv Neuroradiol Source Type: research
Same-eye comparison of pupillary dilation with an intraoperative standardized intracameral combination of mydriatics (Mydrane®) versus a preoperative ophthalmic (Mydriasert®) in standard cataract surgery in non-diabetic patients. J Fr Ophtalmol. 2019 Aug 19;: Authors: de Faria A, Giorgi R, Cohen Salmon M, Bonnel S, Holweck G, Le Corre A, Chazalon E Abstract INTRODUCTION: Cataract surgery is the most commonly performed surgery in the world, and its success depends in part on the quality of mydriasis. PURPOSE: To compare, for the same eye, the pupillary dilation obtained with Mydrane® (st...
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
HIGH blood pressure is a common condition in the UK. Making certain lifestyle tweaks can help to lower a soaring reading. According to a recent study, a popular juice may also do the trick.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSION: High Galectin-3, MMP-9, and ST-2 are independently influenced to a certain degree by demographic, clinical and laboratory characteristics. However, no single characteristic was found to be commonly associated with all of the three biomarkers. PMID: 31438834 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
TYPE 2 diabetes is a life-long condition that requires a person to overhaul aspects of their lifestyle to avert the risks. Mike Trenell, founder and CEO of changing Health sheds a light on a vital yet too often overlooked area of diabetes management - behavioural science.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Becky Hay, 46, from Basingstoke, Hampshire was diagnosed with high blood pressure in 2017, and started taking medication. But within days of taking ramipril, she developed a bad cough.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 23 August 2019Source: American Journal of Kidney DiseasesAuthor(s): Enrico Fiaccadori, Carmela Cosola, Alice Sabatino
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
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