APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC

Triple negative breast cancer (TNBC) is a breast cancer subgroup characterized by a lack of hormone receptors ’ expression and no HER2 overexpression. These molecular features both drastically reduce treatment ...

Source: Journal of Experimental and Clinical Cancer Research - July 15, 2019 Category: Cancer & Oncology Authors: Matilde Clarissa Malfatti, Lorenzo Gerratana, Emiliano Dalla, Miriam Isola, Giuseppe Damante, Carla Di Loreto, Fabio Puglisi and Gianluca Tell Tags: Research Source Type: research