Nebulized Antibiotics Epithelial Lining Fluid Concentrations Overestimate Lung Tissue Concentrations

“…measuring [lung] epithelial lining fluid antibiotic concentrations in patients receiving inhaled antibiotics is not an appropriate method for assessing lung tissue concentrations.”
Source: Anesthesiology - Category: Anesthesiology Source Type: research

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In this study, anesthesia/surgery impaired cognition, demonstrated by an increase escape latency and reduction in the number of platform crossings in Morris water maze (MWM) trials, through activating microglia neuroinflammation and decreasing PSD-95 expression. However, pretreatment with MS-275 attenuated postoperative cognitive impairment severity. Furthermore, pretreatment with MS-275 decreased activated microglia levels and increased PSD95 protein expression in the hippocampus. Pretreatment with MS-275 reduced NF-κB-p65 protein expression and nuclear accumulation as well as the neuroinflammatory response (product...
Source: Neuroscience - Category: Neuroscience Source Type: research
AbstractAn adult male jungle cat (Felis chaus) weighing 6  kg with the history of inability to bearing weight on its left forelimb was presented. Physical examination and radiography revealed transverse radio-ulna fracture and carpal subluxation. Internal fixation with plate was chosen for treatment. On the day of surgery, anesthesia was induced with intr amuscular ketamine (10 mg/kg) and midazolam (0.3 mg/kg). Brachial plexus block (BPB) was performed using lidocaine (3 mg/kg) and bupivacaine (0.75 mg/kg) mixture guided by an electrical nerve stimulator. During the surgery, anesthesia was maintain...
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research
ConclusionThe nontourniquet combined with controlled hypotension technique can alleviate chronic pain and promote the long-term rehabilitation of patients after TKA.
Source: Journal of Anesthesia - Category: Anesthesiology Source Type: research
Publication date: Available online 17 August 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): Claire E. Adams, Michael DobsonAbstractThere is a discrepancy between healthcare need and the ability to provide safe anaesthesia in low/low-middle income countries (LMICs). There is a shortage of medically trained anaesthetists. Most anaesthetics are provided by non-physician anaesthetists who may not have studied the core sciences underpinning anaesthesia, but are clinically very competent. Poor infrastructure is common, such as a shortage of piped medical gases and critical care beds. Safe anaesthesia depends on e...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Chairman of UA's anesthesiology department steps down over leadership concerns Dr. Randal Dull will remain as tenured professor and physician at the UA. tucson.com
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums
Publication date: Available online 22 July 2019Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Berthold Bein, Jochen RennerLess invasive or even completely non-invasive haemodynamic monitoring technologies have evolved during the last decades. Even established, invasive devices such as the pulmonary artery catheter and transpulmonary thermodilution have still an evidence-based place in the perioperative setting, albeit only in special patient populations. Accumulating evidence suggests to use continuous haemodynamic monitoring, especially flow-based variables such as stroke volume or cardiac output t...
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
This article describes challenges through reflection on personal experience in Zambia.
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
This article provides an understanding of the choice of anaesthetic and analgesic drugs used in a low-resourced setting with a focus on those used less commonly in a well-resourced setting.
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Authors: Murt A, Dincer MT, Karaca C, Seyahi N PMID: 31416387 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Hello! Current CA3 in the northeast region looking at non-fellowship jobs. It seems like the area where I want to be is either academic or AMC jobs. I have been looking into this AMC job that was bought by Mednax about 3-4 years ago. Reading through forums, there seems to be concern for private practice jobs where new grads might be screw over if a group gets purchase by AMC while they are on the partnership track. Is there a concern after the group is already bought and appears stable... Mednax Job
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums
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