Cerebellar Dysfunction and Schizophrenia: From “Cognitive Dysmetria” to a Potential Therapeutic Target

American Journal of Psychiatry,Volume 176, Issue 7, Page 498-500, July 01, 2019.
Source: American Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research

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Less than half of individuals who were seen in an emergency department (ED) in Ontario for a mental health –related issue had a follow-up visit with a physician within two weeks after discharge, according to astudy published today inPsychiatric Services in Advance. Those who had a substance use disorder were even less likely to have a follow-up visit with a physician during this period compared with those who did not have a substance use disorder, the study found.“Whether individuals present voluntarily because of subjective distress or involuntarily (for example, with police escort) because of acute risk, psyc...
Source: Psychiatr News - Category: Psychiatry Tags: bipolar disorder emergency department follow-up visit Lucy Barker Ontario Psychiatric Services in Advance schizophrenia serious mental illness substance use disorders Source Type: research
  The rent is due tomorrow; but then you’ll be left with only $10 for the week’s groceries. What do you do? Many people panic over money (or the lack of it), but for those of us with mental illness, it can feel like a life or death situation: It can trigger an even greater anxiety attack and/or depression. Or it may mean not being able to afford the medication that keeps you well enough to work. What can be done? In this Not Crazy episode, Gabe and Jackie discuss how you can gain a sense of control in these situations, and Jackie shares her own big money scare. (Transcript Available Below) SUBSCRIBE &a...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General LifeHelper Mental Health and Wellness Money and Financial Not Crazy Podcast Stress Source Type: blogs
Authors: Sreeraj VS, Bose A, Chhabra H, Shivakumar V, Agarwal SM, Narayanaswamy JC, Rao NP, Kesavan M, Varambally S, Venkatasubramanian G Abstract Combining cognitive retraining with transcranial direct current stimulation (tDCS) has been hypothesized to improve cognitive deficits in schizophrenia. The effect of combining a neuropsychological/psychophysiological task with tDCS, called "online-tDCS" for cognitive enhancement in schizophrenia is not rigorously assessed. In this proof-of-concept study, we aimed at evaluating the effect of a single session online-tDCS on working memory(WM) and its transferabi...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
This study investigated the effect of ketamine on the expression of ErbB4 (considered a schizophrenia candidate gene) in the hippocampus and prefrontal cortex of rats. Rats were randomly divided into four groups: control, low-dose, medium-dose and high-dose groups. The low-dose, medium-dose and high-dose groups were intraperitoneally injected with 15  mg/kg, 30 mg/kg and 60 mg/kg ketamine, respectively, twice a day (9:00 a.m. and 9:00 p.m.); the control group was administered normal saline. The treatment lasted 7 days. After treatment, rats were euthanized, and their brain tissues were collected and the...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
Source: Neuropsychiatric Disease and Treatment - Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research
Authors: Chow TJ, Tee SF, Loh SY, Yong HS, Abu Bakar AK, Tang PY PMID: 32078952 [PubMed - as supplied by publisher]
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Publication date: Available online 21 February 2020Source: Prostaglandins, Leukotrienes and Essential Fatty AcidsAuthor(s): Sergej Nadalin, Suzana Jonovska, Vesna Šendula Jengić, Alena Buretić-TomljanovićABSTRACTThe available data suggest that abnormalities of arachidonic acid-related signaling may be of relevance in attenuated niacin-induced flush responses and lipid and glucose metabolism disturbances, which are all common among individuals with schizophrenia. We previously demonstrated attenuated skin flush responses to niacin in patients with schizophrenia. Here we investigated whether these niacin responses ...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) - Category: Lipidology Source Type: research
In this non-interventional study, the functionality and well-being of patients with schizophrenia with aripiprazole once-monthly (AOM) was evaluated under real-life conditions in a naturalistic population.
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
AbstractPoor mental health remains a significant source of morbidity and mortality in the Bhutanese refugee community. Mental Health First Aid (MHFA) is a promising intervention that has been used in other immigrant communities to prepare individuals to recognize and respond to mental health warning signs. This was a non-randomized program evaluation. Using pre- and post-training questionnaires developed for prior evaluations of MHFA, we examined the effectiveness of training offered with and without culturally-appropriate orientation to mental health terminology and concepts (N  = 458). Pre- to post-training...
Source: Journal of Immigrant and Minority Health - Category: International Medicine & Public Health Source Type: research
ConclusionData revealed a gap between concepts and emotional and cognitive experiences. Both professional and experiential language and knowledge have to be considered as complementary. Consequently, the ICD should be co-constructed by professionals, service users, and carers. It should take the emotional component of language, and the diversity of linguistic and cultural contexts, into account.
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research
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