Validity and Utility of the Center for Epidemiological Studies Depression Scale for Detecting Depression in Family Caregivers of Persons with Dementia.
CONCLUSIONS: CES-D is a valid and reliable scale for detecting caregiver depression in dementia. It has added utility, beyond that of a caregiver burden scale, in identifying a subgroup of caregivers with depression but not burden. However, two subscales (Positive affect and Interpersonal problems) may require caution in interpretation among non-Caucasian caregivers. PMID: 31307034 [PubMed - as supplied by publisher]
Conclusion: Blood transfusion, especially transfusion of any type of red blood cells is associated with an increased risk of dementia.
Conclusion: Although data on the associations between apathy and frailty are scarce, these conditions potentially shares physiological mechanisms and were found to be closely associated. Temporal association between frailty and apathy deserve to be further investigated. PMID: 31411039 [PubMed - as supplied by publisher]
AbstractThe soluble amyloid protein procurer α (sAPPα) and β (sAPPβ) have been postulated as promising new cerebrospinal fluid (CSF) biomarkers for Alzheimer’s disease (AD) and multiple other neurodegenerative diseases, but have failed to meet expectations with their often discordant and even contradictory findings to date. The aim of th e study was to systematically explore this issue. Cochrane Library, PubMed, and CNKI were systematically searched without language or date restrictions. This network meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (P...
Conclusion: Interventions directed at the promotion of the QoL of patients with mild AD should focus on the promotion of mindfulness skills in AD patients, in addition to the reduction of psychological morbidity and the promotion of functionality, awareness of the disease, family relationships and social support. PMID: 31411042 [PubMed - as supplied by publisher]
This study shows that providing high quality of care for persons with dementia, and providing caregiver support and education, can make a difference in health outcomes that are important to people,” Reuben said.Study co-authors are Dr. Zaldy Tan, Tahmineh Romero and Dr. Neil Wenger of UCLA; Emmett Keeler of Rand Corp.; and Dr. Lee Jennings of the University of Oklahoma.The study was funded by the National Institutes of Health ’s National Institute on Aging, the National Institutes of Health/National Center for Advancing Translational Science UCLA CTSI, the Commonwealth Fund, the Centers for Medicare&Medicai...
This report describes the general study design and highlights lessons learned and future directions. In particular, drawing on lessons learned from this clinical research, a community-based prospective cohort study is currently under way among older adults in Panama to validate a blood-based biomarker profile for detecting mild cognitive impairment and Alzheimer's disease, as well as risk factors for cognitive decline. KEYWORDS: Dementia, biomarkers, Latin America, aging, cognition, chronic disease, Panama. PMID: 31401637 [PubMed - in process]
Purpose of review Physicians treating patients with Parkinson disease must evaluate not only motor symptoms but also acquire expertise in assessing the complex behavioral features that often accompany the disease, such as dementia, apathy, anxiety, and depression. Recent findings There is a risk of diagnostic confusion and error because many of the behavioral and motor symptoms accentuate, overlap, or mimic each other. Summary Awareness of potential diagnostic pitfalls and "pseudo-syndromes" should lead to more accurate clinical assessment and better care for our patients.
Conclusion: Older age, less education, and more cognitive impairment decreased the likelihood of completion. However, psychometric test results indicate that those who completed the LoCB understood the questions, even with severe cognitive impairment. We conclude, therefore, that the LoCB is applicable for investigating control orientation among people with dementia. PMID: 31402698 [PubMed - as supplied by publisher]
Neuropsychiatric symptoms (NPS) are now recognized as a major component of neurocognitive disorders, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD). NPS in dementia, also referred to as behavioral and psychological symptoms of dementia (BPSD), can take various forms, including: psychotic symptoms, mood disturbances (e.g., depressive symptoms and anxiety), and socially inappropriate behaviours.1,2 NPS are highly prevalent in the course of these disorders, with a large cross-sectional study reporting up to 80% of individuals exhibiting a clinically significant neuropsychiatric manifestation after onset of...
Conclusion: Better VRQoL was independently associated with reduced depressive symptoms. Supporting older people in aged care to maintain optimal levels of vision-specific functioning, independence, and emotional well-being may protect their mental health. PMID: 31392896 [PubMed - as supplied by publisher]