Dose-rate-independent and diffusion-free nanoclay-based radio-fluorogenic gel dosimeter

We report a nanoclay-based radiofluorogenic gel (NC-RFG) dosimeter employing dihydrorhodamine 123 (DHR 123), which avoids the main drawbacks of conventional RFG, namely, diffusion of the radiation products, dose rate dependence, and oxygen effects in radiation-induced reactions. The dose responses of the NC-RFG employing DHR 123 under X-ray irradiation were evaluated using a fluorescence spectrometer and 2D fluorescence gel scanner. The results show high linearity within the range 0–5 Gy, and the sensitivity was maintained by increasing the post-irradiation time to 37 days and the dose rate from 3.0 to 10.4 Gy/min. We also discussed the preparation conditions for the clay and radiosensitizers, trichloroacetic acid (TCAA) and Triton X-100. By scanning with a commercially available 2D fluorescence scanner, the 2D dose distribution can be evaluated as it has a linear dose response, and its spatial dose information is maintained for up to 73 days.Graphical Abstract
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research

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The accuracy of magnetic resonance imaging (MRI) for prostate cancer detection has been demonstrated in multiple studies, but the interpretation of prostate MRI can be quite challenging. In particular, changes caused by aging (ie, hyperplasia) or by pathologic conditions such as inflammation or cancer can lead to a nearly singular appearance on MRI for each prostate. Additionally, the lack of robust standardization across MRI scanners hampers the adoption of quantitative parameters for imaging analysis.
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Conclusions: 3D semiautomatic quantification of PPV is feasible and reproducible using CT in patients with occupational exposure to asbestos. PPV measurement may be useful to correlate with other asbestos-related disease outcomes and prognosis.
Source: Journal of Thoracic Imaging - Category: Radiology Tags: Original Articles Source Type: research
Just a fun thought that crossed my mind after reading about some admissions scandals. We spend a lot of time and money to get to the point of applying. If one could sell a med school acceptance or pay their way into an acceptance, how much do you think they'd go for?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Medical - MD Source Type: forums
Publication date: Available online 22 August 2019Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Inga Gabriunaite, Aušra Valiūnienė, Margarita Poderyte, Arunas RamanaviciusAbstractRecently, self-assembled monolayers (SAMs) are gaining a lot of interest due to their simplicity of preparation and wide applicability in the development of model systems used in pharmaceutical and biomedical analysis. The most efficient methods used for the investigation of SAM-based structures usually include cyclic voltammetry and electrochemical impedance spectroscopy. Scanning electrochemical microscopy (SECM) co...
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Currently brain injuries like concussion are diagnosed using CT scans which do not work well and only pick up bleeds in the brain.The new way of testing would allow people access to proper treatment sooner.
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Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
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Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
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Source: Materials Science in Semiconductor Processing - Category: Materials Science Source Type: research
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