Diversification of small RNA amplification mechanisms for targeting transposon-related sequences in ciliates [Developmental Biology]

The silencing of repetitive transposable elements (TEs) is ensured by signal amplification of the initial small RNA trigger, which occurs at distinct steps of TE silencing in different eukaryotes. How such a variety of secondary small RNA biogenesis mechanisms has evolved has not been thoroughly elucidated. Ciliated protozoa perform small...

Source: Proceedings of the National Academy of Sciences - July 15, 2019 Category: Science Authors: Masatoshi Mutazono, Tomoko Noto, Kazufumi Mochizuki Tags: Biological Sciences Source Type: research