Melanoblasts as Multipotent Cells in Murine Skin.

Melanoblasts as Multipotent Cells in Murine Skin. Methods Mol Biol. 2019;1879:257-266 Authors: Motohashi T, Kunisada T Abstract Melanoblasts (MBs) are melanocyte precursors that are derived from neural crest cells (NCCs). We recently demonstrated the multipotency of MBs; they differentiate not only into pigmented melanocytes but also other NCC derivatives. We herein describe methods for the isolation of MBs from mouse skin by flow cytometry. Methods to culture isolated MBs that retain their multipotency and isolation methods for MBs using gene-modified mouse are also described. PMID: 30006864 [PubMed - indexed for MEDLINE]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research