Generation and Analysis of Viral Vector-Mediated Rodent Models for Parkinson's Disease.

Generation and Analysis of Viral Vector-Mediated Rodent Models for Parkinson's Disease. Methods Mol Biol. 2019;1948:271-286 Authors: Karikari AA, Koprich JB, Ip CW Abstract The use of viral vector-mediated α-synuclein-overexpressing rodent models for Parkinson's disease has become increasingly accepted to study associated pathology and to use as a platform for therapeutic efficacy testing. We here describe methods to generate such models and how to analyze them by behavioral assessments, histological investigations, and examination of nigrostriatal dopaminergic function. PMID: 30771185 [PubMed - indexed for MEDLINE]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research

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Publication date: Available online 22 September 2020Source: Brain, Behavior, and ImmunityAuthor(s): Sahabuddin Ahmed, Mohit Kwatra, Samir Ranjan Panda, USN Murty, VGM Naidu
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Conditions:   Parkinson Disease;   Oculomotor; Disorder Interventions:   Other: Control Group;   Other: Oculomotor Training Group Sponsors:   The Hong Kong Polytechnic University;   University of California, Berkeley;   University of Melbourne Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Follow up;   Parkinson Disease;   Rehabilitation Interventions:   Other: Exercise+FU;   Other: Active Comparator group Exercise Sponsor:   Somogy Megyei Kaposi Mór Teaching Hospital Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Last week I introduced you to the idea of Storming the Castle but I’d be the first to admit not everyone wants to change their own world let alone change THE world and these posts aren’t for those people. Instead they are for that small minority of people who do want to create change, whether it’s in their own life or whether it’s for the benefit of others and incidentally, as you’ll begin to see, those two things are not mutually exclusive. Many others who have come before me will tell you that it is a lonely road when you are storming a castle and it can feel a bit like you’re in a fi...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Happiness change Source Type: news
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Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Tags: Short communication Source Type: research
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