Co-expression of C/EBP γ and ATF5 in mouse vomeronasal sensory neurons during early postnatal development

We examined the trans-acting effects of C/EBPγ and ATF5 on V2r transcription and found that the co-expression of C/EBPγ and ATF5, but not C/EBPγ or ATF5 alone, increased Vmn2r66 promoter reporter activity via the C/EBP:ATF response element (CARE) in Neuro2a cells. These results suggest the role of C/EBPγ on ATF5-regulated VSN differentiation in early postnatal development.
Source: Cell and Tissue Research - Category: Cytology Source Type: research