A Study to Evaluate the Efficacy, Safety and Tolerability of Bermekimab in Patients With Hidradenitis Suppurativa

Conditions:   Hidradenitis Suppurativa;   Acne Inversa;   Suppurative Hidradenitis Interventions:   Drug: bermekimab;   Drug: placebo Sponsor:   XBiotech, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
This article provides an overview of hidradenitis suppurativa, lichen planus, lichen sclerosis, calcinosis cuti, pyogenic granuloma, intertrigo, and seborrheic keratosis. This article also focuses on recognition and management of these pleomorphic afflictions of the perianal region. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Clinics in Colon and Rectal Surgery - Category: Surgery Authors: Tags: Review Article Source Type: research
Introduction: Acne inversa (hidradenitis suppurativa), a chronic inflammatory skin disease, has been associated with impaired quality of life. There are various measuring systems to assess physical severity; however, there are no specific quality of life questionnaires for this disease in the Spanish language.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Introduction: Hidradenitis suppurativa (HS) and psoriasis have been linked to cardiovascular disease. There is currently a deficiency in the literature regarding the prevalence of clinically important cardiovascular diseases that arise in patients with HS in a United States population. We sought to determine the odds of stroke, coronary artery disease (CAD), heart failure (HF), and peripheral artery disease (PAD) in patients with HS compared with patients with psoriasis and controls.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Introduction: Hidradenitis suppurativa (HS) and psoriasis has been linked to cardiovascular disease. There is currently a deficiency in the literature regarding the prevalence of clinically important cardiovascular diseases that arise in patients with HS in a United States population. We sought to determine the odds of stroke, coronary artery disease (CAD), heart failure (HF), and peripheral artery disease (PAD) in patients with HS compared with patients with psoriasis and controls.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Hidradenitis suppurativa (HS) is a chronic, debilitating, skin disorder characterized by immune activation and dysregulation. Yet, little is known about the relationship between HS and other inflammatory or autoimmune disorders. We sought to determine the comorbid autoimmune disorders associated with HS in US adults and children. Data from the 2002-2012 National Inpatient Sample were analyzed, including a representative 20% sample of all US hospitalizations. Multivariable survey logistic regression models were constructed with HS and autoimmune disorders as the binary independent and dependent variables, respectively, and ...
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
We present real-world data from a tertiary HS clinic with regard to the efficacy and safety of adalimumab up to 52 weeks.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Background: Hidradenitis suppurativa (HS) is associated with bacterial colonization, skin barrier disruption, immune dysregulation, and use of topical and/or oral antibiotics and immunosuppressing treatments that can increase the risk of infection
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Patients with hidradenitis suppurativa (HS) experience chronic inflammation of the skin with disease exacerbations associated with increased pain, which may necessitate acute treatment. During such exacerbations, patients with HS often present to the emergency department (ED). However, it is unknown if the disease is correctly identified and coded by health care professionals in the ED. A retrospective, single center institutional board review approved chart review of patients who had at least one diagnosis code for “hidradenitis suppurativa” at any time and who received treatment with analgesics for HS-related...
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Background: Hidradenitis suppurativa (HS) is a chronic, debilitating dermatological condition with recurrent abscesses and scarring. Such physical manifestations can impair the emotional well-being. The purpose is to assess the mental wellbeing of HS patients.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
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