Persistent HIV DNA in spinal fluid may be associated with cognitive challenges

(University of California - Los Angeles Health Sciences) HIV DNA remained in the cerebrospinal fluid of half of participants with well-managed HIV (virologic suppression in the plasma), confirming that the central nervous system (CNS) is a major reservoir for latent HIV. Individuals who harbored HIV DNA in the cerebrospinal fluid were more likely than other study participants to experience cognitive deficits on neurocognitive testing.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news