B lymphocytes directly contribute to tissue fibrosis in IgG4-Related Disease

The present work unveils unanticipated fibrogenic properties of B lymphocytes in humans and demonstrates their direct contribution to tissue fibrosis in the pathogenesis of IgG4-related disease.

Source: Journal of Allergy and Clinical Immunology - July 14, 2019 Category: Allergy & Immunology Authors: Emanuel Della-Torre, Elena Rigamonti, Cory Perugino, Simona Baghai Sain, Na Sun, Naoki Kaneko, Takashi Maehara, Lucrezia Rovati, Maurilio Ponzoni, Raffaella Milani, Marco Lanzillotta, Vinay Mahajan, Hamid Mattoo, Ivan Molineris, Vikram Deshpande, John H. Source Type: research