Healthy Lifestyle Offsets Genetic Risk for Dementia Healthy Lifestyle Offsets Genetic Risk for Dementia

Adhering to a healthy lifestyle reduces the chances of developing dementia, even among those at genetic risk for dementia, new research suggests.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Psychiatry News Source Type: news

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Publication date: Available online 23 August 2019Source: SeizureAuthor(s): Alessandro Orsini, Angelo Valetto, Veronica Bertini, Mariagrazia Esposito, Niccolò Carli, Berge A. Minassian, Alice Bonuccelli, Diego Peroni, Roberto Michelucci, Pasquale StrianoAbstractProgressive Myoclonus Epilepsies (PMEs) are a group of uncommon clinically and genetically heterogeneous disorders characterised by myoclonus, generalized epilepsy, and neurological deterioration, including dementia and ataxia. PMEs may have infancy, childhood, juvenile or adult onset, but usually present in late childhood or adolescence, at variance from epil...
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 23 August 2019Source: Alzheimer's &DementiaAuthor(s): Carla M. Startin, Sarah Hamburg, Rosalyn Hithersay, Tamara Al-Janabi, Kin Y. Mok, John Hardy, Andre Strydom
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Authors: Ma F, Lv X, Du Y, Chen H, Liu S, Zhao J, Gao Y, An P, Zhou X, Song A, Sun C, Wang G, Ji Y, Wang X, Xu W, Huang G Abstract BACKGROUND: Leukocyte telomere length (LTL) is associated with the aging process and age-related degenerative diseases. The relation of peripheral blood LTL to mild cognitive impairment (MCI) and Alzheimer's disease (AD) and the role of folate and homocysteine (Hcy) in this relation remain unclear. OBJECTIVES: We aimed to investigate the association between LTL and the risks of MCI/AD, and to explore whether folate and Hcy may play a role in this association. METHODS: This case-...
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Authors: Li B, He Y, Ma J, Huang P, Du J, Cao L, Wang Y, Xiao Q, Tang H, Chen S Abstract OBJECTIVE: Gut microbiota changes before the onset of Alzheimer's disease (AD) and the alterations could be detected in the stage of mild cognitive impairment (MCI). The findings might offer diagnostic biomarkers before the onset of dementia. BACKGROUND: AD is the most common cause of dementia, and MCI is the predementia state. Recent studies suggest the alterations in the gut microbial communities associated with AD, whereas the microbiota in MCI before the onset of dementia has not been discovered and characterized in hum...
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
ConclusionsThis population-based retrospective cohort study provides evidence that patients newly-diagnosed with dementia who showed higher initial drug compliance or maintained antidementia drugs (Cholinesterase inhibitors and memantine) would benefit in total health-care costs.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
ConclusionThe MRAC research methods performed close to that of CTAC in the quantitative evaluation of [18F]FDG uptake and z-scores. Among the clinically implemented MRAC methods, DixonBone should be preferred for diagnostic assessment of dementia with [18F]FDG PET/MRI. However, as artifacts occur in DixonBone attenuation maps, they must be visually inspected to assure proper quantification.
Source: EJNMMI Research - Category: Radiology Source Type: research
AbstractLantana camara Linn. (Verbenaceae) is used traditionally for its numerous medicinal properties such as antimalarial, antibacterial, anticancer and anti-inflammatory. In the present study, we investigated the chemical composition of essential oil from the leaves ofL. camara (LCEO) occurring in the Republic of Benin (West Africa) in comparison with LCEOs from other regions; evaluated its sedative effects in mice via inhalation administration; and identified the compounds responsible for activity. LCEO was extracted by hydrodistillation and chemical analyses of the oil were performed by GC and GC/MS. The oil was domin...
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research
Photo credit Jeremy Wong Dementia and the loss of a spouse are sad and challenging enough on their own, but when they coincide, the result can be truly heartbreaking. For many adult children, deciding whether to inform a cognitively impaired parent that their spouse has died is a serious and often recurring struggle. For someone who has not experienced such a dilemma, this would appear to be a no-brainer. However, as with many dementia-related quandaries, the question and answer are far more complex for those facing this reality. Support a caregiver or jump-start discussion in support groups with real stories - for bu...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
(Reuters Health) - Family caregivers for dementia patients don't sleep as long or as well as other adults of the same age, a new study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Conclusions: Persons with dementia and their families were willing to enroll in an in-home telemedicine clinic. Satisfaction with home visits was high and equal to in-clinic visits. Clinical implications: Video telemedicine is a promising dementia service delivery model for rural patients and others for whom travel to a specialty clinic is burdensome. Abbreviations: ADL: Activities of Daily Living; Home-CVT: Home Clinical Video Telehealth; iADL: Instrumental Activity of Daily Living; GRECC: The New England Geriatric Research Education and Clinical Center; IM: Instant Messaging; LTC: long term care; THT: Telehealth Technici...
Source: Clinical Gerontologist - Category: Geriatrics Tags: Clin Gerontol Source Type: research
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