New Research Highlights Urgent Need for Early Alzheimer ’s Disease Detection and Intervention 

“In my case, symptoms began to appear when I was only 57. In fact, the doctors believe early-onset Alzheimer’s has a strong genetic predictor, and that it may have been progressing for some years before I was diagnosed.” – Pat Summitt  Anyone who’s gone through the experience of a loved one developing Alzheimer’s disease and progressively deteriorating to a shell of their former selves knows how devastating this brain disease is for both patient and those who love and care for him or her.  Memory Performance Changes May Show Up in 20s with Family History of Alzheimer’s Startlingly, as the latest research shows, Alzheimer’s disease risk isn’t confined to older individuals. Changes in memory performance may start showing up in men and women in their 20s if they come from families with Alzheimer’s disease history. Indeed, deficits in memory and thinking are the first clinical presentations of this progressive neurological disorder. According to the research from the Translational Genomics Research Institute, such higher risk is more pronounced in men with a family history of the disease, as well as among those who have diabetes, are carriers of a common genetic chain in APOE, a gene that is associated with Alzheimer’s disease risk, and those who may have a lower educational attainment. What makes this risk even more concerning, however, is the fact that there is currently no cure for Alzheimer’s di...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Aging Alzheimer's Memory and Perception Alzheimer's disease Dementia Source Type: blogs

Related Links:

Date: Wednesday, 09 18, 2019; Speaker: Robert A. Star, MD, Director, Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, NIH; Building: Building 10 (Clinical Center); Lipsett Amphitheater
Source: NIH Calendar of Events - Category: American Health Source Type: events
Authors: Crabtree E, Brest B, Lewis RK Abstract Suicidality is a serious concern in this country. In the U.S. nearly 40,000 people die by suicide each year. It is the 10th leading cause of death. For those 15-24, it is the 2nd leading cause of death. Using data from the Add Health Longitudinal data set and data gathered from a local organization an examination of suicidality among African American youth was conducted. Given the trauma and low resourced situations many African American adolescents find themselves in, interventions are needed to address these health concerns before other issues such as education and ...
Source: Journal of Prevention and Intervention in the Community - Category: International Medicine & Public Health Tags: J Prev Interv Community Source Type: research
This study was designed to measure the perceived stress among Whites and Nonwhites using the Perceived Stress Scale, the Center for Epidemiologic Studies Depression Scale Revised, Positive and Negative Affect Scale (PANAS) and other behavioral indicators (diet and nutrition) to determine the overall well-being of college students. College students attending a mid-sized University in the Midwest completed an 80 item online survey. The results showed that thirty-six percent of the sample displayed depressive symptoms, 10% of the respondents endorsed high perceived stress and 56% reported experiencing moderate stress levels. ...
Source: Journal of Prevention and Intervention in the Community - Category: International Medicine & Public Health Tags: J Prev Interv Community Source Type: research
Publication date: Available online 22 August 2019Source: Neuroscience ResearchAuthor(s): John M. Andraka, Naveen Sharma, Yannick MarchalantAbstractMost neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, demonstrate preceding or on-going inflammatory processes. Therefore, discovering effective means of counteracting detrimental inflammatory mediators in the brain could help alter aging-related disease onset and progression. Fish oil and marine-derived omega-3, long-chain polyunsaturated fatty acids (LC n-3) have shown promising anti-inflammatory effects both systemically and centrally. More...
Source: Neuroscience Research - Category: Neuroscience Source Type: research
Publication date: Available online 21 August 2019Source: Neurochemistry InternationalAuthor(s): Jingxi Ma, Peifeng Qiao, Qin Li, Yangyang Wang, Lan Zhang, Liang-Jun Yan, Zhiyou CaiAbstractThe Food and Drug Administration has approved vagus-nerve stimulation (VNS) for the treatment of patients with epilepsy, depression, and headache. By targeting diverse neuroprotective and neuroplasticity pathways, VNS has the potential to be expanded as a treatment for ischemic stroke. VNS has been found to attenuate infarct volume, reduce neurological deficits, and improve memory and cognition in rats with stroke injuries. Some pilot stu...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
Publication date: Available online 21 August 2019Source: Molecular and Cellular NeuroscienceAuthor(s): Ju Gao, Luwen Wang, Tingxiang Yan, George Perry, Xinglong WangAbstractGenetic mutations in TAR DNA-binding protein 43 (TDP-43) cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Importantly, TDP-43 proteinopathy, characterized by aberrant phosphorylation, ubiquitination, cleavage or nuclear depletion of TDP-43 in neurons and glial cells, is a common prominent pathological feature of various major neurodegenerative diseases including ALS, FTD, and Alzheimer's disease (AD). Although the pathomechan...
Source: Molecular and Cellular Neuroscience - Category: Neuroscience Source Type: research
In conclusion, this multicenter study demonstrated an association between preoperative smoking and increased risk of infection following new DBS implantation surgery. Counseling about this risk should be considered in preoperative evaluation of patients who are considering undergoing a DBS procedure.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Authors: Duffy IR, Boyle AJ, Vasdev N Abstract Machine learning (ML) algorithms have found increasing utility in the medical imaging field and numerous applications in the analysis of digital biomarkers within positron emission tomography (PET) imaging have emerged. Interest in the use of artificial intelligence in PET imaging for the study of neurodegenerative diseases and oncology stems from the potential for such techniques to streamline decision support for physicians providing early and accurate diagnosis and allowing personalized treatment regimens. In this review, the use of ML to improve PET image acquisiti...
Source: Molecular Imaging - Category: Radiology Tags: Mol Imaging Source Type: research
– Somryst app by Pear Therapeutics Digital therapeutics have potential but commercial success unproven (Vantage): “Developing drugs to treat disorders of the central nervous system is famously fraught with difficulty. Several companies, including Pear Therapeutics and Dthera, are taking a wildly different approach: digital therapeutics. These are pieces of software designed to treat disease that are regulated, prescribed and even paid for as if they were drugs … Pear is so far the only company to have brought a digital therapeutic to market – but it is by no means the only company in this space. Ak...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology Akili Interactive AKL-T01 Click Therapeutics cognitive dysfunction digital therapeutics Dthera Pear Therapeutics Somryst Source Type: blogs
ConclusionAlmost six out of ten VS patients had fatigue, significantly higher than the control group. Interest and focus on fatigue in VS patients can improve the patient ’s QoL.
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research
More News: Alzheimer's | Amnesia | Anxiety | Brain | Budgets | Cataracts | Clinical Trials | Computers | Dementia | Depression | Diabetes | Education | Endocrinology | Environmental Health | Genetics | Geriatrics | Neurology | Psychology | Sports Medicine | Study | Women