Elevated indoleamine-2,3-dioxygenase enzyme activity in a novel mouse model of HIV-associated atherosclerosis

Conclusion: These results indicate that Tg26+/−/ApoE−/− serve as a new mouse model for HIV-induced atherogenesis, and aid in understanding the role of tryptophan catabolism in the pathogenesis of HIV atherosclerosis/CVD.
Source: AIDS - Category: Infectious Diseases Tags: BASIC SCIENCE Source Type: research