Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury

ConclusionThis research is the first to clarify that iridoid glycosides and phenol compounds are the substance basis of the hepatoprotective activity of the EAFVC. Establish rapid and effective method for the determination of main seven compounds, which is vital for the quality control of V. ciliata. These main compounds could be chosen to the analytical marker of V. ciliata. The strong activity of EAFVC and its isolated compounds on relieving the drug-induced liver injury provided the further scientific data for the traditional use and deep development of this Tibetan Medicine. In addition, PASS Online prediction, an effective way, maybe used to auxiliarily screen and analyse the active ingredients from the traditional medicine.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research