Can cell-free DNA testing be used in pregnancies with increased nuchal translucency?

CONCLUSION: cfDNA does not appear to be the appropriate genetic test in fetuses with a NT above the 99th centile, given that 12-19% of the genetic anomalies were undetectable with the current tests. Additionally, 6.6% of fetuses will have a major structural abnormality identifiable using first-trimester ultrasound. This article is protected by copyright. All rights reserved.
PMID: 31301176 [PubMed - as supplied by publisher]

Source: The Ultrasound Review of Obstetrics and Gynecology - July 12, 2019 Category: Radiology Authors: Miranda J, Paz Y Miño F, Borobio V, Badenas C, Rodriguez-Revenga L, Pauta M, Borrell A Tags: Ultrasound Obstet Gynecol Source Type: research