Mechanisms of Vascular Permeability and Remodeling Associated with Hemarthrosis in Factor VIII-Deficient Mice.

CONCLUSIONS: Intact hemostasis at the time of hemarthrosis and during healing are both critical to prevent vascular remodeling, which appears worse with severe and prolonged FVIII deficiency. Unbiased RNA sequencing revealed potential targets for intervention and biomarker development to improve management of HA. This article is protected by copyright. All rights reserved. PMID: 31301687 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31301687?dopt=Abstract

Source: Thrombosis and Haemostasis - July 12, 2019 Category: Hematology Authors: Cooke EJ, Wyseure T, Zhou JY, Gopal S, Nasamran CA, Fisch KM, Manon-Jensen T, Karsdal MA, Mosnier LO, von Drygalski A Tags: J Thromb Haemost Source Type: research