Engineered 3D Model of Cancer Stem Cell Enrichment and Chemoresistance.

CONCLUSION: Our integrated approach illustrates the utility of the serial passage spheroid model for examining the emergence and development of chemoresistance in ovarian cancer in a controllable and reproducible format.
PMID: 31299607 [PubMed - as supplied by publisher]

Source: Neoplasia - July 8, 2019 Category: Cancer & Oncology Authors: Ward Rashidi MR, Mehta P, Bregenzer M, Raghavan S, Fleck EM, Horst EN, Harissa Z, Ravikumar V, Brady S, Bild A, Rao A, Buckanovich RJ, Mehta G Tags: Neoplasia Source Type: research