The novel inhibitor PRI-724 for Wnt/ β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice.
Conclusions: These results suggest that the β-catenin/CBP inhibitor PRI-724 is a potent antifibrotic agent that acts by modulating the activity of macrophages in the lungs.
PMID: 31298961 [PubMed - as supplied by publisher]
Source: Experimental Lung Research - Category: Respiratory Medicine Tags: Exp Lung Res Source Type: research
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