Modeling the role of carrier and mobile herds on foot-and-mouth disease virus endemicity in the Far North Region of Cameroon

We present a spatial stochastic model of disease dynamics that incorporates a spatial transmission kernel in a modified Gillespie algorithm, and use it to evaluate two hypothesized drivers of endemicity: asymptomatic carriers and the movement of mobile herds. The model is parameterized using data from the pastoral systems in the Far North Region of Cameroon. Our computational study provides evidence in support of the hypothesis that asymptomatic carriers, but not mobile herds, are a driver of endemicity.Graphical abstract
Source: Epidemics - Category: Epidemiology Source Type: research

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The objectives of this study were (i) to develop a reliable method, applicable in biomonitoring, for the rapid detection of infectious oocysts by cell culture of their sporocysts combined with qPCR (sporocyst-CC-qPCR), and (ii) to adapt this method to blue and zebra mussels experimentally contaminated by oocysts with the objective to use these organisms as sentinels of aquatic environments. Combining mechanical treatment and bead beating leads to the release of 84 ± 14% of free sporocysts. The sporocyst-CC-qPCR can detect fewer than ten infectious oocysts in water within four days (one day of contact and three days ...
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research
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Source: Nature Reviews Neurology - Category: Neurology Authors: Source Type: research
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Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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