A Retrospective Chart Review of Screening on the Prevalence of Metabolic Syndrome (MetS) in an Irish Community Mental Health Service.

A Retrospective Chart Review of Screening on the Prevalence of Metabolic Syndrome (MetS) in an Irish Community Mental Health Service. Issues Ment Health Nurs. 2019 Jul 11;:1-7 Authors: Cocoman AM, Gallagher D Abstract Individuals who are treated with antipsychotic medications are at risk of developing metabolic syndrome (MetS). The comorbidity of a severe mental illness (SMI) and a physical illness has a major impact on the quality of life of these individuals. We conducted a retrospective chart review (RCR) of 214 individuals with a diagnosis of schizophrenia who had been receiving antipsychotic medications for at least 6 months, in five clinical settings in an Irish community mental health service. The aim was to determine the presence of MetS to assist in improving screening practices and directing future practice. The National Cholesterol Education Program High Blood Cholesterol Adult Treatment Panel 111 (NCEP ATP 111) metabolic diagnostic criteria were utilised to determine prevalence. After examining 214 charts we observed that waist circumference varied from 68 to 142 cm, elevated waist circumference over the recommended parameters was recorded in 145 charts. Forty-five percent (n = 98) had blood pressure (BP) readings over 130/85. The range for body mass index (BMI)'s varied from 16 to 54, BMIs over 25 was recorded in 44% (n = 95) of charts. Elevated triglycerides (TG) were recorded in 37% (n =&thin...
Source: Issues in Mental Health Nursing - Category: Nursing Tags: Issues Ment Health Nurs Source Type: research

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This study is a prospective, randomized, single-centered, patient-assessor-blinded, parallel-controlled clinical pilot trial. In all, 36 patients will be randomized to an experimental group or control group by a 1:1 ratio. All patients will receive lifestyle interventions. The experimental group will receive electroacupuncture treatment. The control group will receive sham electroacupuncture treatment. The primary outcomes are body mass index (BMI) and waist circumference (WC). The secondary outcome measures include blood pressure (BP), fasting blood glucose (FBG), triglycerides (TG), total cholesterol (TC), high-density l...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
DiscussionHMW adiponectin may be a promising biomarker of cardiometabolic health, especially among PwS. Adiponectin is a potential target for lifestyle and pharmacological interventions. Research on the possible role of HMW adiponectin in modifying cardiometabolic pathology in schizophrenia is needed.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
CONCLUSION: Our findings highlight the need for more studies focusing on serum adiponectin level and its relationship with MetS in schizophrenia, particularly in those taking typical antipsychotics. PMID: 31059867 [PubMed - as supplied by publisher]
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
In conclusion, the MetS prevalence was found to be increased among schizophrenia patients over time, and the increase in the young age group was particularly striking. Among all of the factors investigated, nutritional status was found to play a major role in this increased prevalence. PMID: 31030256 [PubMed - as supplied by publisher]
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
In conclusion, the MetS prevalence was found to be increased among schizophrenia patients over time, and the increase in the young age group was particularly striking. Among all of t he factors investigated, nutritional status was found to play a major role in this increased prevalence.
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Neuroscience Source Type: research
This study presents findings from a large sample with extensive clinical phenotyping—allowing us to examine the relationships of insulin resistance with a number of key psychopathological, cognitive, and functioning measures, using multivariate methods to assess the relative contributions of different factors to metabolic abnormalities. PwS often have many risk factors for metabolic abnormalities: lifestyle habits, medications, and underlying biological mechanisms including inflammation and oxidative stress. Treatment and prevention of metabolic abnormalities in PwS can be particularly challenging due to these multip...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: Results of the present study suggest that metabolic syndrome in participants taking second-generation antipsychotics is mediated through OSA. PMID: 30581214 [PubMed]
Source: Indian Journal of Psychiatry - Category: Psychiatry Tags: Indian J Psychiatry Source Type: research
Loneliness is an established risk factor for poor cardiometabolic health. People with psychotic disorders experience high rates of both cardiometabolic disease and loneliness, but how these factors are associated is poorly understood. Thus, using data from the second Australian National Survey of Psychosis we examined whether loneliness is associated with the likelihood of cardiometabolic disorder in psychotic illness. Loneliness was assessed using a single-item measure, with a 4-point scale (not lonely; lonely occasionally; some friends but lonely for company; socially isolated and lonely) whilst cardiometabolic status wa...
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research
Conclusion The relationships between the potency of 5-HT2C blockade and hypertriglyceridemia and the potency of M3 blockade and glucose intolerance were shown in clinical setting. Receptor-binging profiles might be useful to estimate metabolic effect of antipsychotics-treatment. References Meyer JM, Davis VG, Goff DC, et al. Change in metabolic syndrome parameters with antipsychotic treatment in the CATIE Schizophrenia Trial: prospective data from phase 1. Schizophr Res. 2008;101: 273–286. Salvi V, Mencacci C, Barone-Adesi F. H1-histamine receptor affinity predicts weight gain with antidepressants. Eur Neuropsychoph...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Letters to the Editor Asenaprine clozapine olanzapine schizophrenia Source Type: research
Conclusion: Patients with schizophrenia are at high risk of metabolic syndrome. It is important to address substance use problems as an important risk factor of this comorbidity.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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