Mouse Hematopoietic Stem Cell Modification and Labelling by Transduction and Tracking Posttransplantation.

Mouse Hematopoietic Stem Cell Modification and Labelling by Transduction and Tracking Posttransplantation. Methods Mol Biol. 2019;1940:129-142 Authors: Cao B, Li S, Pritchard C, Williams B, Nilsson SK Abstract The tracking of the hematopoietic potential of genetically manipulated fluorescent hematopoietic stem cells (HSC) in the bone marrow (BM) allows the assessment of regulatory processes involved in the re-establishment of hematopoiesis posttransplant. Herein, we describe the means to assess the consequence of expressing specific genes in HSC on their engraftment potential posttransplant. PMID: 30788822 [PubMed - indexed for MEDLINE]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research