MiR-216a-5p targets TCTN1 to inhibit cell proliferation and induce apoptosis in esophageal squamous cell carcinoma.

Conclusions: Our results demonstrate that miR-216a-5p might serve as a tumor suppressor in ESCC cells through negatively regulating TCTN1 expression, indicating the possibility that miR-216a-5p and TCTN1 might be attractive targets for ESCC therapeutic intervention. PMID: 31297133 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31297133?dopt=Abstract

Source: Mol Biol Cell - July 13, 2019 Category: Molecular Biology Authors: Chai L, Yang G Tags: Cell Mol Biol Lett Source Type: research