NHS Choices 'Behind the Headlines' assessment of press reports that a "new antiviral may help in flu fight"
Source: NHS Choices Area: News The 'Behind the Headlines' service from NHS Choices has featured a quality assessment of press reports that a 'flu drug shows promise in overcoming resistance' (BBC news and other; 22nd Feb 2013). The reports are based on early stage laboratory and animal research, which examined the effectiveness of a possible new antiviral treatment for flu. It was found in the laboratory to be similarly or more effective than zanamivir at stopping the influenza virus from spreading between cells, including strains with demonstrated resistance to oseltamivir and zanamivir. The chemical was also similarly effective to zanamivir at prolonging survival in mice infected with a lethal dose of influenza. The authors of the quality assessment discuss the research design, results, the authors' conclusions, and how these findings should be interpreted (see the link below for details). They say that although this new chemical has the potential to be developed into an antiviral ...
Publication date: Available online 8 October 2020Source: Microbes and InfectionAuthor(s): Keisuke Nishioka, Michihito Kyo, Takaaki Nakaya, Nobuaki Shime
ConclusionsPatients on various solid tumour treatments achieve sero-protection rate congruent with the general population. The sero-protection HIA titres were not sustained at 24 weeks postvaccination.
Comparison of deaths from the coronavirus (COVID-19) with deaths from influenza (flu) and pneumonia. Includes deaths by date of death occurrence and breakdowns by sex and age.
CONCLUSIONS: Promoting asthma self-management education, influenza vaccinations, nebulizers, and spacers can decrease the frequency of healthcare utilization and asthma-related expenditures while improving medication adherence. PMID: 33031709 [PubMed - as supplied by publisher]
CONCLUSIONS: Our results underscore how erroneous reporting of 1 condition can lead to underreporting of other causes of death. Misapplication or misunderstanding of procedures by medical providers, rather than extrinsic factors influencing the reporting process, are key drivers of erroneous cause-of-death reporting. PMID: 33031711 [PubMed - as supplied by publisher]
Publication date: Available online 7 October 2020Source: The Annals of Thoracic SurgeryAuthor(s): Rony Atoui, Fady Ebrahim F, Kevin Saroka, John Mireau, Janet E. McElhaney, Gregory Hare
Since its emergence the impact of COVID-19 has been profound, and the public health challenge seem to be the most serious seen in a respiratory virus since the 1918 H1N1 influenza pandemic (Soper 1919). Following its emergence in Wuhan, cases of COVID-19 were exported outside of China, mainly by travelers using the global aviation networks (Wu et al., 2020). It should be noted that transboundary spread of viruses is quite common in veterinary medicine (Klausner et al., 2015, 2017, 2018).
The COVID-19 pandemic exerts inflammation-related parasympathetic complications and post-infection manifestations with major inter-individual variability. To seek the corresponding transcriptomic origins for the impact of COVID-19 infection and its aftermath consequences, we sought the relevance of long and short non-coding RNAs (ncRNAs) for susceptibility to COVID-19 infection. We selected inflammation-prone men and women of diverse ages among the cohort of Genome Tissue expression (GTEx) by mining RNA-seq datasets from their lung, and blood tissues, followed by quantitative qRT-PCR, bioinformatics-based network analyses ...
Publication date: Available online 7 October 2020Source: American Journal of Infection ControlAuthor(s): Peng-jun Lu, Anup Srivastav, Tammy A. Santibanez, Ashley Amaya, Jill A. Dever, Jessica Roycroft, Marshica Stanley Kurtz, Walter W. Williams