Differences in clinico-pathological characteristics and outcomes between proteinase 3-ANCA positivity and myeloperoxidase-ANCA positivity in lupus nephritis.

CONCLUSION: MPO-ANCA-positive LN patients had more severely impaired baseline renal function and less active lupus serology. More severely chronic pathological changes, including interstitial fibrosis and tubular atrophy on renal specimens, occurred in MPO-ANCA-positive LN patients. We found that MPO-ANCA-positive LN patients had worse renal outcomes. PMID: 31291845 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31291845?dopt=Abstract

Source: Lupus - July 9, 2019 Category: Rheumatology Authors: Li C, Wang JJ, Zhou ML, Liang DD, Yang J, Zhu HX, Hu WX, Zhang HT Tags: Lupus Source Type: research

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