Activation of GPR30 with G1 attenuates neuronal apoptosis via src/EGFR/stat3 signaling pathway after subarachnoid hemorrhage in male rats.

CONCLUSION: G1 reduced EBI through attenuating neuronal apoptosis after SAH in male rats, partly via activating src/EGFR/stat3/signaling pathway. G1 may provide a promising therapeutic strategy for SAH patients. PMID: 31295444 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31295444?dopt=Abstract

Source: Experimental Neurology - July 7, 2019 Category: Neurology Authors: Peng J, Zuo Y, Huang L, Okada T, Liu S, Zuo G, Zhang G, Tang J, Xia Y, Zhang JH Tags: Exp Neurol Source Type: research