Plasma osteopontin levels, but not its myocardial expression, reflect heart failure severity in recently diagnosed dilated cardiomyopathy.

CONCLUSION: Plasma OPN levels reflect heart failure severity in patients with Ro-DCM. Myocardial OPN expression is not associated with either plasma OPN levels or markers of heart failure in these individuals. PMID: 31289910 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research

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Investigations in dilated cardiomyopathy Chest X-ray PA view will assess the cardiac size in dilated cardiomyopathy and show evidence of pulmonary congestion. Sick persons may present with features of frank pulmonary edema in the form of hilar haze or bat wing pattern of pulmonary edema. Significant left ventricular dysfunction can exist without much of cardiomegaly on chest X-ray as well. ECG may show sinus tachycardia, left atrial overload and sometimes left ventricular hypertrophy. A wide QRS complex with left bundle branch block pattern may indicate potential benefit from cardiac resynchronization therapy (CRT). ECG ...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs
Publication date: Available online 23 March 2019Source: Revista Portuguesa de Cardiologia (English Edition)Author(s): Maria Emanuel Amaral, Pedro Epifânio, Natália Noronha, António Pires, Paula Martins, Vanda Azevedo, Eduardo Castela, Manuel J. AntunesAbstractAnomalous origin of the left coronary artery from the pulmonary artery is a rare congenital heart defect and a cause of myocardial ischemia during childhood. Most undiagnosed cases die in the first year of life as an extensive collateral network is essential for survival. The diagnosis requires a high index of clinical suspicion. The authors presen...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
AbstractThe aim of this study was to determine non-invasive diagnostic markers by echocardiography that differentiate ischemic dilated (ICM) from non-ischemic dilated cardiomyopathy (NICM) in patients with new onset heart failure. We identified 100 consecutive new heart failure patients with dilated cardiomyopathy (valvular etiology excluded). Clinical risk factors, medication history, serum biomarkers, ECG and echocardiographic variables were compared between the ICM and NICM groups (as confirmed by coronary angiography). Mean age, left ventricular size and ejection fraction were 56 years, 6.1  cm and 26% respectivel...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
Time limit: 0 Quiz-summary 0 of 20 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Information This test series requires login for attempting. You can login easily with your Facebook account (Use the CONNECT WITH icon on the upper part of right sidebar displaying t...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs
This case report illustrates challenging aspects of diagnosis of isolated cardiac sarcoidosis. Here, we present a 69-year-old female who had been diagnosed as dilated cardiomyopathy before was admitted to our hospital for congestive heart failure. Coronary angiography showed no significant abnormalities. Left ventriculography revealed left ventricular aneurysm. The endomyocardial biopsy specimens showed no significant findings. Cardiac MRI showed late enhancement at the lateral wall of the left ventricle, this finding suggested the presence of cardiac sarcoidosis.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research
AbstractAim We carried out this study to investigate mid-term effects of cardiac resynchronization therapy (CRT) on right ventricular (RV) function and neurohormonal response, expressed by N-terminal pro-brain natriuretic peptide (NT-proBNP), in heart failure patients stratified by baseline RV ejection fraction (RVEF).Methods and ResultsThirty-six patients with nonischemic dilated cardiomyopathy underwent technetium-99m radionuclide angiography with bicycle exercise immediately after CRT implantation (during spontaneous rhythm and after CRT activation) and 3 months later. Plasma NT proBNP was assessed before implantation...
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
This study assessed the prevalence of grey hair in patients with coronary artery disease and whether it was an independent risk marker of disease. This was a prospective, observational study which included 545 adult men who underwent multi-slice computed tomography (CT) coronary angiography for suspected coronary artery disease. Patients were divided into subgroups according to the presence or absence of coronary artery disease, and the amount of grey/white hair. The amount of grey hair was graded using the hair whitening score: 1 = pure black hair, 2 = black more than white, 3 = black equals white, 4 = white more t...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion LVNC should be looked for at any dilated cardiomyopathy particularly in young patients. It requires a careful echocardiographic examination and sometimes CMR to confirm the diagnosis. It is characterized by severe systolic and diastolic dysfunction that would provide poor prognosis.
Source: Journal of the Saudi Heart Association - Category: Cardiology Source Type: research
Publication date: Available online 22 November 2016 Source:Journal of Cardiology Cases Author(s): Takayuki Iwano, Kei Yunoki, Noriyuki Tokunaga, Masataka Shigetoshi, Hiroki Sugiyama, Hiroyuki Yamamoto, Jun Kondo, Mikizo Nakai, Masahiro Okada, Hiromi Matsubara A 54-year-old man was transferred to our hospital due to congestive heart failure and left ventricular thrombi. Transthoracic echocardiography (TTE) showed mobile “ball-like” not only left ventricular but also right ventricular thrombi associated with severe impaired left and right ventricular function. Contrast-enhanced computed tomography (CT) and cardi...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
A 59-year-old Filipino man without previous illness was admitted for heart failure (HF). Chest X-ray demonstrated an enlarged cardiac silhouette, with a prominent bulge on the third arch of the left heart border (Panel A). Echocardiography detected dilated cardiomyopathy with decreased left ventricular ejection fraction (LVEF 30%), and three large cystic aneurysmal structures: one at the level of the atrioventricular groove protruding inside the right atrium, and the other two in connection with the left main stem, located between the aorta and the pulmonary trunk (B; Supplementary material online, Video1Supplementary mate...
Source: European Heart Journal - Category: Cardiology Source Type: research
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