Pulmonary function changes following helical tomotherapy in patients with inoperable, locally advanced non-small cell lung cancer

ConclusionsThe decline in pulmonary function indices after helical tomotherapy was of similar magnitude to that observed in studies reporting the effect of conformal radiotherapy on lung function. Diffusion capacity was the parameter showing the largest decrease following radiation therapy as compared to baseline and correlated with gross tumor volume. None of the alterations in pulmonary function tests were associated with the lung volume receiving low-dose radiation.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research