Serious Misdiagnosis - Related Harms Mostly Due to ‘ Big Three ’

Vascular events, infections, cancers account for 74.1 percent of high - severity misdiagnosis - related harms
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news

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Joanna Mikulak1,2, Elena Bruni1,2, Ferdinando Oriolo1,2, Clara Di Vito1 and Domenico Mavilio1,2* 1Unit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Milan, Italy 2Department of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy The liver is considered a preferential tissue for NK cells residency. In humans, almost 50% of all intrahepatic lymphocytes are NK cells that are strongly imprinted in a liver-specific manner and show a broad spectrum of cellular heterogeneity. Hepatic NK (he-NK) cells play key roles in tuning liver immune response in b...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conclusions This review describes how leukocyte-heparanase can be a double-edged sword in tumor progression; it can enhance tumor immune surveillance and tumor cell clearance, but also promote tumor survival and growth. We also discuss the potential of using heparanase in leukocyte therapies against tumors, and the effects of heparanase inhibitors on tumor progression and immunity. We are just beginning to understand the influence of heparanase on a pro/anti-tumor immune response, and there are still many questions to answer. How do the pro/anti-tumorigenic effects of heparanase differ across different cancer types? Does...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Andrew R. Crowley1 and Margaret E. Ackerman1,2* 1Molecular and Cellular Biology Program, Dartmouth College, Hanover, NH, United States2Thayer School of Engineering, Dartmouth College, Hanover, NH, United States The field of HIV research relies heavily on non-human primates, particularly the members of the macaque genus, as models for the evaluation of candidate vaccines and monoclonal antibodies. A growing body of research suggests that successful protection of humans will not solely rely on the neutralization activity of an antibody's antigen binding fragment. Rather, immunological effector functions pro...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
The National Institutes of Health (NIH) would receive $34.4 billion in FY 2020, roughly $4.7 billion or 13 percent below the levels enacted by Congress for FY 2019, according to the President’s Budget released on March 11. The budget for NIH includes $492 million in funding made available through the 21st Century Cures Act and $150 million in mandatory funding. The leading biomedical research agency in the world would receive budget cuts across the board. All NIH centers are slated for budget reductions: National Cancer Institute: -8.7 percent National Heart, Lung, and Blood Institute: -14 percent National Inst...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
A man in London has become only the second person to achieve remission from HIV infection, researchers from the UK reported Tuesday. The therapy responsible has worked on only one other person who is considered to be “cured” of HIV: Timothy Ray Brown, who still does not show signs of the virus in his body after more than 10 years. Here’s what to know about the landmark case. How did it happen? In a letter published in the journal Nature, researchers led by Ravindra Gupta from the University of Cambridge London and Imperial College London and his colleagues say that they used a treatment similar to the one...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized HIV/AIDS Source Type: news
About 1.1 million Americans currently live with HIV, and approximately 40,000 are infected each year, according to federal data. But in his State of the Union address, President Donald Trump promised to “eliminate the HIV epidemic in the United States within 10 years” — a plan that hinges on a multi-agency push for better diagnosis, treatment and prevention in at-risk communities, health officials said Wednesday. Trump introduced the plan during his annual address on Tuesday but offered few details. Health officials fleshed out the plan during a call with reporters on Wednesday. The initiative will be ove...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime HIV/AIDS onetime Source Type: news
Funding Opportunity RFA-AI-18-054 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to promote collaborative biomedical research between the United States and Brazil under the U.S.-Brazil Biomedical Collaborative Research Program. Research areas supported under this program include allergy, immunology, and infectious diseases, including HIV/AIDS and its co-morbidities; cancer; mother-to-child transmission of HIV and other congenital infections, early infant diagnosis and treatment; HIV/AIDS in relation to mental health; and neurological disorders and stroke.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Plans restrict coverage of drugs indicated for cancer less often than drugs indicated for other diseases
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news
Scorching sun, ice-cold beverages, light naps in a poolside beach bed. The time for summer vacation has finally arrived, and you cannot even think of anything else just some margaritas in the pool bar. We collected the best digital technologies for you, so you don’t have to worry about emergency situations or your health on holiday. Have a great vacation! 1) Protect your skin with wearable patches! Although we have to wait a bit until nanoparticles make their way into UV-light absorbing sunscreens and anti-aging products, health apps and wearables already line up to save your skin from looking red potatoes the next d...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Health Sensors & Trackers Patients chatbot dermatology digital health food allergy food sensor health chatbot holiday summer technology telemedicine Source Type: blogs
UCLA-led research finds that internet search terms and tweets related to sexual risk behaviors can predict when and where syphilis trends will occur.Two studies from the UCLA-based University of California Institute for Prediction Technology, in collaboration with the Centers for Disease Control and Prevention, or CDC, found an association between certain risk-related terms that Google and Twitter users researched or tweeted about and subsequent syphilis trends that were reported to the CDC. The researchers were able to pinpoint these cases at state or county levels, depending on the platform used.“Many of the most s...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
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