Interferon β and Anti-PD-1/PD-L1 Checkpoint Blockade Cooperate in NK Cell-Mediated Killing of Nasopharyngeal Carcinoma Cells.

In conclusion, combination of IFNβ and anti-PD-1, augmenting cytotoxicity of NK cells against NPC cells, could be a strategy to improve NPC-directed therapy and warrants further evaluation in vivo. PMID: 31295651 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31295651?dopt=Abstract

Source: Translational Oncology - July 7, 2019 Category: Cancer & Oncology Authors: Makowska A, Braunschweig T, Denecke B, Shen L, Baloche V, Busson P, Kontny U Tags: Transl Oncol Source Type: research