Nonhemolysis of epidemic El Tor biotype strains of Vibrio cholerae is related to multiple functional deficiencies of hemolysin A

ConclusionsMechanisms responsible for nonhemolysis of the epidemic O1 El Tor strains are complex and not only confined to gene mutation but also deficiencies of transcription and extracellular transport of HlyA. Mutations in gene regulation and protein secretion systems of HlyA in the nonhemolyticV. cholerae strains should be areas of concern in future studies.

http://link.springer.com/10.1186/s13099-019-0316-7

Source: Gut Pathogens - July 11, 2019 Category: Microbiology Source Type: research