Highly oxygenated isoprenylated cyclohexanoids from the fungus Parastagonospora nodorum SN15

Publication date: October 2019Source: Phytochemistry, Volume 166Author(s): Amr El-Demerdash, Grégory Genta-Jouve, Margot Bärenstrauch, Caroline Kunz, Emmanuel Baudouin, Soizic PradoAbstractThe chemical investigation of the wheat plant pathogen Parastagonospora nodorum SN15 led to the purification of seven highly oxygenated acetylenic cyclohexanoids named stagonosporynes A-G. Their structures were determined on the basis of extensive NMR and the relative and absolute configurations by an array of computational methods including simulation of NOESY spectrum and electronic circular dichroism (ECD). All compounds were evaluated for their herbicidal activity and stagonosporyne G displayed the most significant herbicidal activity.Graphical abstract

Source: Phytochemistry - July 12, 2019 Category: Chemistry Source Type: research