Thwack! Insects feel chronic pain after injury
(University of Sydney) Scientists have known insects experience something like pain since 2003, but new research published today from Associate Professor Greg Neely and colleagues at the University of Sydney proves for the first time that insects also experience chronic pain that lasts long after an initial injury has healed.
Childhood sexual abuse (CSA) is a physical assault upon the body and considered to be a complex traumatic experience affecting both body and mind. Growing evidence indicates that long-term effects of CSA include maladies such as chronic pain and fibromyalg...
CONCLUSIONS: We were able to define predictors of admission for patients having LH/RAH managed with an ERAS pathway. Increased ASA physical status, being African American, and increased length of procedure were significantly associated with admission after LH/RAH performed under an ERAS pathway. In addition, the incidences of urgent clinic and ER visits, readmissions, and reoperations within 90 days of surgery were similar for patients who were discharged on the day of surgery compared to those admitted. PMID: 31425219 [PubMed - in process]
Abstract BACKGROUND: As opioid abuse and addiction have developed into a major national health crisis, prescription of opioids for pain management has become more controversial. However, opioids do help some patients by providing pain relief and improving the quality of life. To better understand the addictive properties of opioids under chronic pain conditions, we used a conditioned place preference (CPP) paradigm to examine the rewarding properties of morphine in rats with persistent nociception. METHODS: Spared nerve injury (SNI) model was used to induce persistent nociception in rats. Nociceptive behavior...
ConclusionsA simple noninvasive protocol for managing cTMD with self-help, exercises, and oral devices resulted in clinically and statistically meaningful improvements in pain, function, and quality of life.
Patients with hidradenitis suppurativa (HS) experience chronic inflammation of the skin with disease exacerbations associated with increased pain, which may necessitate acute treatment. During such exacerbations, patients with HS often present to the emergency department (ED). However, it is unknown if the disease is correctly identified and coded by health care professionals in the ED. A retrospective, single center institutional board review approved chart review of patients who had at least one diagnosis code for “hidradenitis suppurativa” at any time and who received treatment with analgesics for HS-related...
Introduction: Hidradenitis suppurativa (HS) has been shown to have a negative impact on quality of life, even more so than psoriasis, acne and eczema. Research has only recently focused on the impact HS has on sexual health. HS patients may experience sexual decline due to pain, physical appearance, and diminished sexual desire. Dermatologists who treat this chronic condition are in a unique position to screen these patients for sexual health concerns and provide counseling or specialized referral
Background: Atopic dermatitis (AD), is a chronic inflammatory dermatological disease that is characterized by eczematous skin lesions with symptoms including intense itching and pain, and signs including erythema, dryness, scaling flaking, thickening and fissuring. These signs/symptoms can have a significant impact on patients ’ health-related quality of life (HRQoL). AD is common in children and adolescents, affecting up to 17% of school children (aged 5-18) in the United States (US); however published qualitative literature on the patient experience of AD in adolescents is minimal.
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the folliculopilosebaceous units. It is characterized by recurrent inflammatory nodules that may progress to draining sinuses with scar formation. HS often results in severe pain, disability, and disfigurement. It appears that genes play a role in HS, with an estimated 40% of patients having an affected first-degree family member. Research on a few families documents an autosomal dominant pattern of inheritance, but HS remains poorly understood without any large-scale genetic evaluations to date.
This study aimed to qualitatively explore the adult experience of AD.
Psoriasis is a chronic, systemic, inflammatory disease involving skin, nails, and joints. Nail psoriasis may lead to many difficulties in daily activities including work and impairment in quality of life and may also be the cause of severe pain, anxiety and depression. A 66-year-old woman with a history of seronegative arthritis receiving methotrexate presented with severe ungual dystrophy affecting all 20 nails. Clinical examination revealed subungual hyperkeratosis, salmon patches, periungual erythema, onycholysis and nail crumbling.