Human cartilage homogenates influence the crystallization of monosodium urate (MSU) and the inflammatory response to MSU crystals: a potential link between osteoarthritis and gout

ConclusionsIn the presence of elevated urate, human cartilage homogenates increase MSU crystal formation and promote the formation of smaller crystals which have greater inflammatory potential. These processes may contribute to the predilection of gout to osteoarthritic joints.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatology - July 10, 2019 Category: Rheumatology Authors: Ashika Chhana, Bregina Pool, Yicheng Wei, Ally Choi, Ryan Gao, Jacob Munro, Jillian Cornish, Nicola Dalbeth Tags: Full Length Source Type: research