Association between Physical Inactivity and Health-Related Quality of Life in Adults with Coronary Heart Disease

Coronary heart disease (CHD) is a major cause of death worldwide [1]. It is characterized by cholesterol-containing deposits in the major heart blood vessels, which results in angina, shortness of breath, fatigue and myocardial infarction [2]. The number of survivors is growing due to an aging population, and advancement in CHD treatment and management [3,4]. Most of the research on survivorship has focused on morbidity and mortality, however there is increasing awareness that quality of life (QoL) is also an important health indicator [5,6].
Source: Maturitas - Category: Primary Care Authors: Source Type: research

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Source: OnMedica Latest News - Category: UK Health Source Type: news
(Natural News) Hypercholesterolemia is a well-known risk factor for cardiovascular disease and the main contributor to coronary heart disease. High levels of low-density lipoprotein (LDL-C), for instance, are associated with the risk of atherosclerosis and heart attack. Treatments for these conditions, therefore, focus mainly on reducing total cholesterol and LDL-C levels in the blood. In a...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Publication date: Available online 1 July 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Kausik K Ray, Helen M Colhoun, Michael Szarek, Marie Baccara-Dinet, Deepak L Bhatt, Vera A Bittner, Andrzej J Budaj, Rafael Diaz, Shaun G Goodman, Corinne Hanotin, Robert A Harrington, J Wouter Jukema, Virginie Loizeau, Renato D Lopes, Angèle Moryusef, Jan Murin, Robert Pordy, Arsen D Ristic, Matthew T Roe, José TuñónSummaryBackgroundAfter acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1·4–1·...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Authors: Alves-Ferreira J, Rocha-Neves J, Dias-Neto M, F Braga S Abstract Objetives: Carotid endarterectomy (CEA) is an established treatment for carotid stenosis (CS). However, this procedure is not risk-free and it is insufficient to control disseminated atherosclerosis. Our aim was to determine long-term cardiovascular (CV) morbidity and mortality after CEA and identify associated risk predictors. DESIGN: Consecutive cohorts of CEAs performed between 2010-2018 in two Portuguese hospitals were retrospectively analysed. The major end-points were acute myocardial infarction (AMI), stroke, all-cause death and ma...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
This study determine the relative treatment effects of NST on fatal and nonfatal CV events among statin-treated patients. Methods A network meta-analysis based on a systematic review of randomized controlled trials (RCTs) comparing non-statin lipid-modifying agents among statin-treated patients was performed. PubMed, EMBASE, CENTRAL, and Clinicaltrial.gov were searched up to April 10, 2018. The primary outcomes were CV and all-cause mortalities. Secondary CV outcomes were coronary heart disease (CHD) death, non-fatal myocardial infarction (MI), any stroke, and coronary revascularization. Risks of discontinuations were ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Sarah K. Azzam1, Wael M. Osman2, Sungmun Lee1, Kinda Khalaf1, Ahsan H. Khandoker1, Wael Almahmeed3,4, Herbert F. Jelinek5 and Habiba S. Al Safar1,2* 1Biomedical Engineering Department, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates 2Khalifa University Center of Biotechnology, Abu Dhabi, United Arab Emirates 3Institute of Cardiac Science, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates 4Heart and Vascular Institute, Cleveland Clinic, Abu Dhabi, United Arab Emirates 5Australian School of Advanced Medicine, Sydney and School of Community Health, Charles Sturt University, Ma...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Hongfei Gu1†, Shuang Shao2†, Jie Liu3,4,5, Zhenqian Fan2, Yu Chen2, Jingxian Ni3,4,5, Conglin Wang6, Jun Tu3,4,5, Xianjia Ning3,4,5, Yongzhong Lou1*, Bin Li1* and Jinghua Wang3,4,5* 1Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China 2Department of Endocrinology and Metabolism, The Second Hospital of Tianjin Medical University, Tianjin, China 3Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China 4Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, China 5Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration i...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
This study also identified the cardiac myocyte as a significant local source of BDNF, as cardiac myocyte-specific deletion of BDNF induced a similar cardiomyopathy phenotype. While these results do not exclude a role for other neurotrophins, particularly in injury states, they point to the requirement for continued, local synthesis of BDNF to maintain optimal cardiac function. A major, unresolved question relates to how the truncated TrkB isoform (TrkBT1) transduces the inotropic effects of BDNF, which will require additional study. A concurrent study evaluated the potential impact of the BDNF-mediated activation of the k...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Marco Vacante1, Antonio Biondi1, Francesco Basile1, Roberto Ciuni1, Salvatore Luca1, Salomone Di Saverio2, Carola Buscemi3, Enzo Saretto Dante Vicari3 and Antonio Maria Borzì3* 1Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy 2Cambridge Colorectal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom 3Department of Clinical and Experimental Medicine, Specialization School in Geriatrics, University of Catania, Catania, Italy There is a high prevalence of hypothyroidism in the elderly population, mainly among women. The mo...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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