Relative Efficacy of Tegaserod in a Systematic Review and Network Meta-analysis of Licensed Therapies for Irritable Bowel Syndrome with Constipation

Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research

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ConclusionsIn Japan, among the population of under 70  years old, the prevalence of IBS-C and FC (Rome III criteria) was 4.97% and 8.76%, respectively. IBS-C caused more severe symptoms than FC, resulting in impairment of QOL.
Source: Journal of Gastroenterology - Category: Gastroenterology Source Type: research
Source: Clinical and Experimental Gastroenterology - Category: Gastroenterology Tags: Clinical and Experimental Gastroenterology Source Type: research
Gluten? Lactose? Stomach pain? Digestive troubles? Way too many people suffer from gastrointestinal issues, and much less are aware of the digital technologies that can come to their aid. Did you know that digestibles could successfully replace the dreaded colonoscopy? Or have you heard about microbiome testing? What about the swarm of health apps supporting dietary restrictions? We took a deep breath and jumped into the universe of digital technologies just to bring you as much information about the future of gastroenterology as possible. Will you jump after us? IBS, colorectal cancer, and other animals Referring to...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Genomics Health Sensors & Trackers diet dieting digestibles digestion digital health gastro gastroenterologist gastroenterology gastrointestinal gluten gut Innovation lactose microbiome stomach techno Source Type: blogs
AbstractBackgroundFunctional constipation (FC) and constipation-predominant irritable bowel syndrome (IBS-C) have significant healthcare impact. Clinical and investigative data of patients with these disorders in Indian population is scarce. We aimed to compare the clinical and anorectal manometric profile of patients with FC and IBS-C.MethodsConsecutive patients with chronic constipation undergoing  anorectal manometry (ARM) and balloon expulsion test (BET) were enrolled. Thirty healthy volunteers served as controls (HC). Functional defecatory disorder (FDD) was diagnosed according to ROME IV criteria if both ARM and...
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
You're reading 5 Surprising Things Stress Can Do to Your Body, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. You just got off a terrible meeting, your boss gave you an impossible deadline for the next project, your team is pushing you to make extra hours, and you still need to pick up the kids at school. Your body is in a “fight or flight response.” Your stress levels are high, you feel your breath get quicker and even feel your heart beating faster than usual. Although this is all a natural response from y...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness self improvement stress Source Type: blogs
This study aimed to objectively investigate whether the addition of polydextrose to sterilized probiotic containingLactobacillus helveticus will confer benefits to constipation-predominant irritable bowel syndrome patients.MethodsA total of 163 patients were randomized into two groups: Group A to consume 350  mL of sterilized probiotic with 5.85 g polydextrose daily for 1 week and Group B without polydextrose. Intestinal transit time, fecal pH, fecal weight, and modifiedGarrigues questionnaires for pre- and post-consumption were assessed.ResultsMedian intestinal transit time was significantly reduced from 58...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Effect of moxibustion on the expression of GDNF and its receptor GFRα3 in the colon and spinal cord of rats with irritable bowel syndrome. Acupunct Med. 2019 Jun 12;:acupmed2017011455 Authors: Qi Q, Wu H, Jin X, Jin D, Wang Y, Wang C, Liu Y, Wang X Abstract BACKGROUND: Moxibustion treatment has been found to ameliorate clinical symptoms including abdominal pain, diarrhoea and constipation in patients with irritable bowel syndrome (IBS). Herein we investigated the mechanisms underlying the use of moxibustion in a rat model of IBS. METHODS: In our study, an IBS model was established in rats b...
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - Category: Complementary Medicine Authors: Tags: Acupunct Med Source Type: research
Publication date: Available online 29 April 2019Source: Best Practice &Research Clinical GastroenterologyAuthor(s): P. Benno, E. Norin, T. Midtvedt, P.M. HellströmAbstractBy administering an anaerobic cultivated human intestinal microbiota (ACHIM) via upper gastrointestinal route using endoscopy we aimed to rectify intestinal dysbiosis and simultaneously achieve a treatment response in IBS patients. The study population fulfilled the Rome III IBS criteria and comprised 50 patients. During 10 days, patients recorded the irritable bowel syndrome symptom severity scale (IBS-SSS) along with the Bristol stool scale and...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
This study aimed to investigate the clinical features of patients with both NCCP and constipated functional bowel disorders (FBD). Among 692 consecutive patients diagnosed with functional constipation or irritable bowel syndrome with constipation and underwent anorectal manometry (ARM) in our hospital, PPI-refractory NCCP was present in 37. The clinical course of various torso symptoms including NCCP and ARM findings were retrospectively evaluated. The mean age was lower in the NCCP than in the non-NCCP group (57.4 vs 61.3 years, respectively, Pā€Š=ā€Š.042). Back pain (16.2% vs 2.0%, Pā€Š
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
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